Evidence map›Paper›PMID 28137780›Full record

ArticleThe Journal of cell biology2017

Clari Valansi, David Moi, Evgenia Leikina, Elena Matveev, Martín Graña, Leonid V Chernomordik, Héctor Romero, Pablo S Aguilar, Benjamin Podbilewicz

Open access · bronzeAbstract readComment
In one paragraph

Article in The Journal of cell biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 108 citations in OpenAlex.

  1. Article
  2. Characterization ofbioRxiv : the preprint server for biology · 2026
    Article
  3. The SPARK complex forms the molecular basis of vertebrate fertilization.bioRxiv : the preprint server for biology · 2026
    Article
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  15. Review
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  18. Review
  19. DMP8 and 9 regulate HAP2/GCS1 trafficking for the timely acquisition of sperm fusion competence.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  20. Article

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 4 countries.

Clari ValansiDepartment of Biology, Technion- Israel Institute of Technology, Haifa 32000, Israel.
David MoiLaboratorio de Biología Celular de Membranas, Instituto de Investigaciones Biotecnologicas "Dr. Rodolfo A. Ugalde," Universidad Nacional de San Martin, Buenos Aires, CP1650, Argentina.
Evgenia LeikinaSection on Membrane Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892.
Elena MatveevDepartment of Biology, Technion- Israel Institute of Technology, Haifa 32000, Israel.
Martín GrañaUnidad de Bioinformática, Institut Pasteur Montevideo, Montevideo 11400, Uruguay.ORCID 0000-0003-1182-8236
Leonid V ChernomordikSection on Membrane Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892.
Héctor RomeroLaboratorio de Organización y Evolución del Genoma, Unidad de Genómica Evolutiva, Departamento Ecología y Evolución, Facultad de Ciencias/Centro Universitario Regional del Este, Universidad de la República, Montevideo 11400, Uruguay.ORCID 0000-0001-9685-0584
Pablo S AguilarLaboratorio de Biología Celular de Membranas, Instituto de Investigaciones Biotecnologicas "Dr. Rodolfo A. Ugalde," Universidad Nacional de San Martin, Buenos Aires, CP1650, Argentina paguilar@iib.unsam.edu.ar podbilew@technion.ac.il.
Benjamin PodbilewiczDepartment of Biology, Technion- Israel Institute of Technology, Haifa 32000, Israel paguilar@iib.unsam.edu.ar podbilew@technion.ac.il.ORCID 0000-0002-0411-4182
Technion – Israel Institute of Technology · ILNational Institutes of Health · USNational University of General San Martín · ARInstitut Pasteur de Montevideo · UYUniversidad de la República de Uruguay · UY

Funding

Protein-mediated membrane remodelingZIAHD001501 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI CHERNOMORDIK, LEONID V. · 2009 to 2025
$30.7M
6 · The paper itself

Abstract

Cell-cell fusion is inherent to sexual reproduction. Loss of HAPLESS 2/GENERATIVE CELL SPECIFIC 1 (HAP2/GCS1) proteins results in gamete fusion failure in diverse organisms, but their exact role is unclear. In this study, we show that

Indexed as

AnimalsArabidopsisArabidopsis ProteinsCaenorhabditis elegansCaenorhabditis elegans ProteinsCarrier ProteinsCell FusionCell LineCell MembraneCricetinaeGerm CellsMembrane FusionMembrane GlycoproteinsViral Fusion ProteinsArabidopsis ProteinsCaenorhabditis elegans ProteinsCarrier ProteinsEFF-1 protein, C elegansHAP2 protein, ArabidopsisMembrane GlycoproteinsViral Fusion Proteins

Identifiers

PMID28137780
PMCPMC5350521
OpenAlexW2951255526

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.