ArticleMagnetic resonance imaging2017
Reliability of the depth-dependent high-resolution BOLD hemodynamic response in human visual cortex and vicinity.
Article in Magnetic resonance imaging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Pooled it
- Spatial evolution in temporal dynamics of hemodynamic response function in human superior colliculi with ultra-high-resolution MRI at 9.4T.Frontiers in neuroscience · 2026Article
- Towards whole brain mapping of the hemodynamic response function.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2025Article
- Layer-specific BOLD effects in gradient and spin-echo acquisitions in somatosensory cortex.Magnetic resonance in medicine · 2025Article
- Evaluating the capabilities and challenges of layer-fMRI VASO at 3T.Aperture neuro · 2023Article
- Temporal stability of the hemodynamic response function across the majority of human cerebral cortex.Human brain mapping · 2022Article
- Characterization of the blood oxygen level dependent hemodynamic response function in human subcortical regions with high spatiotemporal resolution.Frontiers in neuroscience · 2022Article
- Point-spread function of the BOLD response across columns and cortical depth in human extra-striate cortex.Progress in neurobiology · 2021Article
- Retinotopic variations of the negative blood-oxygen-level dependent hemodynamic response function in human primary visual cortex.Journal of neurophysiology · 2021Article
- Validating Linear Systems Analysis for Laminar fMRI: Temporal Additivity for Stimulus Duration Manipulations.Brain topography · 2021Article
- A temporal decomposition method for identifying venous effects in task-based fMRI.Nature methods · 2020Article
- Dynamics of the cerebral blood flow response to brief neural activity in human visual cortex.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2020Article
- Linear systems analysis for laminar fMRI: Evaluating BOLD amplitude scaling for luminance contrast manipulations.Scientific reports · 2020Article
- More than BOLD: Dual-spin populations create functional contrast.Magnetic resonance in medicine · 2020Article
- Characterization of the hemodynamic response function in white matter tracts for event-related fMRI.Nature communications · 2019Article
- Article
- Characterization of the hemodynamic response function across the majority of human cerebral cortex.NeuroImage · 2018Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Functional magnetic resonance imaging (fMRI) often relies on a hemodynamic response function (HRF), the stereotypical blood oxygen level dependent (BOLD) response elicited by a brief (<4s) stimulus. Early measurements of the HRF used coarse spatial resolutions (≥3mm voxels) that would generally include contributions from white matter, gray matter, and the extra-pial compartment (the space between the pial surface and skull including pial blood vessels) within each voxel. To resolve these contributions, high-resolution fMRI (0.9-mm voxels) was performed at 3T in early visual cortex and its apposed white-matter and extra-pial compartments. The results characterized the depth dependence of the HRF and its reliability during nine fMRI sessions. Significant HRFs were observed in white-matter and extra-pial compartments as well as in gray matter. White-matter HRFs were faster and weaker than in the gray matter, while extra-pial HRFs were comparatively slower and stronger. Depth trends of the HRF peak amplitude were stable throughout a broad depth range that included all three compartments for each session. Across sessions, however, the depth trend of HRF peak amplitudes was stable only in the white matter and deep-intermediate gray matter, while there were strong session-to-session variations in the superficial gray matter and the extra-pial compartment. Thus, high-resolution fMRI can resolve significant and dynamically distinct HRFs in gray matter, white matter, and extra-pial compartments.
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