ArticlePloS one2017
The Association of Lesion Location and Sleep Related Breathing Disorder in Patients with Acute Ischemic Stroke.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Prevalence, Trajectory, and Factors Associated With Patient-Reported Nonmotor Outcomes After Stroke: A Systematic Review and Meta-Analysis.JAMA network open · 2025Pooled it
- SAS-CARE-1 study: stroke topography and polysomnography-based respiratory sleep characteristics.Sleep & breathing = Schlaf & Atmung · 2025Article
- Changes in sleep-disordered breathing severity and post-stroke outcomes in the first year after stroke.Sleep medicine · 2025Article
- Study on the circadian rhythm and sleep state characteristics of patients with acute cerebral infarction accompanied by sleep-breathing disorders.Sleep and biological rhythms · 2024Article
- Prevalence, incidence, and the time trends of sleep-disordered breathing among patients with stroke: a systematic review and meta-analysis.Frontiers in neurology · 2024Review
- Impact of site, size and severity of ischemic cerebrovascular stroke on sleep in a sample of Egyptian patients a polysomnographic study.BMC neurology · 2023Article
- The Diagnostic Value of Gut Microbiota Analysis for Post-Stroke Sleep Disorders.Diagnostics (Basel, Switzerland) · 2023Article
- Sleep-Disordered Breathing in Acute Stroke: A Single-Center, Prospective, Longitudinal Study.Journal of clinical medicine · 2023Article
- Sleep and Stroke: Opening Our Eyes to Current Knowledge of a Key Relationship.Current neurology and neuroscience reports · 2022Review
- Sleep-disordered breathing and cerebral small vessel disease-acute and 6 months after ischemic stroke.Sleep & breathing = Schlaf & Atmung · 2022Observational
- Efficacy and Safety of Acupuncture in the Treatment of Poststroke Insomnia: A Systematic Review and Meta-Analysis of Twenty-Six Randomized Controlled Trials.Evidence-based complementary and alternative medicine : eCAM · 2022Review
- Acupuncture Reduced the Risk for Insomnia in Stroke Patients: A Propensity-Score Matched Cohort Study.Frontiers in aging neuroscience · 2021Article
- Acupuncture for post-stroke insomnia: A protocol for systematic review and meta-analysis.Medicine · 2020Article
- Evaluation of an OSA risk stratifying and treatment protocol during inpatient rehabilitation of post-stroke patients.Sleep & breathing = Schlaf & Atmung · 2020Observational
- Sleep and Stroke: New Updates on Epidemiology, Pathophysiology, Assessment, and Treatment.Current sleep medicine reports · 2019Article
- Sleep-disordered breathing and stroke: chicken or egg?Journal of thoracic disease · 2018Review
- Sex differences in sleep-disordered breathing after stroke: results from the BASIC project.Sleep medicine · 2018Article
- Wake-up stroke is not associated with sleep-disordered breathing in women.Neurology. Clinical practice · 2018Article
- Post-Stroke Sleep-Disordered Breathing-Pathophysiology and Therapy Options.Frontiers in surgery · 2018Review
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimsSleep related breathing disorders (SRBD) are common in patients with ischemic stroke and are associated with poor outcome. SRBD after stroke were assumed to be a direct consequence of injury of specific central nervous system structures. However, whether specific locations of ischemic infarcts cause SRBD is yet unknown. We therefore investigated the association of ischemic lesion location with SRBD.
methodsPatients with acute ischemic stroke treated on our stroke unit were included in a prospective observational study. All patients underwent magnetic resonance imaging (MRI) and polygraphy in the acute phase after stroke. SRBD was defined by an apnea-hypopnea index (AHI) ≥10. MRI were evaluated using standardized maps to depict voxel-wise probability distribution of infarction for patients with and without SRBD. Groups were compared using logistic regression analysis.
resultsOf 142 patients included, 86 (59%) had a SRBD. Age, body mass index and prevalence of arterial hypertension were significantly higher in patients with SRBD. There was no statistically significant association between any lesion location and SRBD.
conclusionWe found no association of lesion location and SRBD in stroke patients, whereas established risk factors for SRBD, known from general population, were significantly associated with SRBD. Given the high prevalence of SRBD in stroke patients, these findings suggest that cerebral ischemia facilitates the occurrence of SRBD in patients with pre-existing risk factors rather than causing it by damaging specific central nervous system structures. Our findings can be used to identify stroke patients who might benefit from polygraphy screening.
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