Evidence map›Paper›PMID 28135261›Full record

ArticleNature nanotechnology2017

Microscopic agents programmed by DNA circuits.

G Gines, A S Zadorin, J-C Galas, T Fujii, A Estevez-Torres, Y Rondelez

Abstract read
PubMed Publisher
In one paragraph

Article in Nature nanotechnology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Signalling and social learning in swarms of robots.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2025
    Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Collective chemomechanical oscillations in active hydrogels.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Catalytic DNA Polymerization Can Be Expedited by Active Product Release.Angewandte Chemie (International ed. in English) · 2022
    Article
  17. Dissipative DNA nanotechnology.Nature chemistry · 2022
    Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

G GinesLIMMS, CNRS, Institute of Industrial Science, University of Tokyo, 153-8505 Tokyo, Japan.
A S ZadorinLaboratoire Gulliver, CNRS, ESPCI Paris, PSL Research University, 10 rue Vauquelin, 75005 Paris, France.
J-C GalasLaboratoire Jean Perrin, CNRS, Université Pierre et Marie Curie, UMR 8237, 4 place Jussieu, 75005 Paris, France.
T FujiiLIMMS, CNRS, Institute of Industrial Science, University of Tokyo, 153-8505 Tokyo, Japan.
A Estevez-TorresLaboratoire Jean Perrin, CNRS, Université Pierre et Marie Curie, UMR 8237, 4 place Jussieu, 75005 Paris, France.
Y RondelezLIMMS, CNRS, Institute of Industrial Science, University of Tokyo, 153-8505 Tokyo, Japan.

Funding

European Research Council 647275
6 · The paper itself

Abstract

Information stored in synthetic nucleic acids sequences can be used in vitro to create complex reaction networks with precisely programmed chemical dynamics. Here, we scale up this approach to program networks of microscopic particles (agents) dispersed in an enzymatic solution. Agents may possess multiple stable states, thus maintaining a memory and communicate by emitting various orthogonal chemical signals, while also sensing the behaviour of neighbouring agents. Using this approach, we can produce collective behaviours involving thousands of agents, for example retrieving information over long distances or creating spatial patterns. Our systems recapitulate some fundamental mechanisms of distributed decision making and morphogenesis among living organisms and could find applications in cases where many individual clues need to be combined to reach a decision, for example in molecular diagnostics.

Indexed as

Models, ChemicalDNADNA

Identifiers

PMID28135261

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.