ArticleNature neuroscience2017
Hormonal gain control of a medial preoptic area social reward circuit.
Article in Nature neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 173 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
173 citing papers in PubMed, 312 citations in OpenAlex.
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- A midbrain circuit for high-fat-food induced conditioned taste aversion.Nature communications · 2026Article
- Sex-specific differences in endocannabinoid regulation of cocaine-evoked dopamine in the medial nucleus accumbens shell.bioRxiv : the preprint server for biology · 2026Article
- Regulation of physical activity and energy expenditure through Phf6 in the medial preoptic area.Nature communications · 2026Article
- A bifunctional optical reporter for tracking estrogen response dynamics in neurons.bioRxiv : the preprint server for biology · 2025Article
- Estrogen modulates reward prediction errors and reinforcement learning.Nature neuroscience · 2025Article
- Biological Mechanisms Balancing Torpor and Reproduction in Mammals.Endocrinology · 2025Review
- Estradiol, via estrogen receptor β signaling, mediates stress-susceptibility in the male brain.Molecular psychiatry · 2025Article
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- Context rescales a social action code in a hormone-sensitive network.bioRxiv : the preprint server for biology · 2025Article
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- How dopamine guides our social world.Pharmacological reviews · 2025Review
- Brain Nuclei in the Regulation of Sexual Behavior, Peripheral Nerves Related to Reproduction, and Their Alterations in Neurodegenerative Diseases: A Brief Review.Brain sciences · 2025Review
- Experience-dependent maternal defense behavior mediated by profrontal cortical projections to the medial preoptic area in mice.Nature communications · 2025Article
- Threat-Driven Social Plasticity: Switch from Innate Attraction to Conditioned Preference.Neuroscience bulletin · 2025Article
- Brain circuits that regulate social behavior.Molecular psychiatry · 2025Review
- Sex-specific hypothalamic neural projection activity drives caregiving in mice.Nature communications · 2025Article
- The effects of social loss and isolation on partner odor investigation and dopamine and oxytocin receptor expression in female prairie voles.Neuropharmacology · 2025Article
113 more citing papers are in PubMed but not listed here.
Corrections and comments
- Correction · 2017-06-30Error in Analyses · · 2 corrections issued on same day for same article
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- Erratum issued
Authors and funding
10 authors at 1 institution in 2 countries.
Funding
Abstract
Neural networks that control reproduction must integrate social and hormonal signals, tune motivation, and coordinate social interactions. However, the neural circuit mechanisms for these processes remain unresolved. The medial preoptic area (mPOA), an essential node for social behaviors, comprises molecularly diverse neurons with widespread projections. Here we identify a steroid-responsive subset of neurotensin (Nts)-expressing mPOA neurons that interface with the ventral tegmental area (VTA) to form a socially engaged reward circuit. Using in vivo two-photon imaging in female mice, we show that mPOA
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.