ArticleJournal of epidemiology2017
Validation of a novel claims-based stroke severity index in patients with intracerebral hemorrhage.
Article in Journal of epidemiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 37 papers.
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Who cites it
37 citing papers in PubMed, 63 citations in OpenAlex.
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- Association of a Cancer Diagnosis and Mortality After Ischemic and Hemorrhagic Stroke and Myocardial Infarction.Neurology · 2026Article
- Clinical outcomes of a generic versus brand-name clopidogrel for secondary prevention in patients with ischemic stroke: a nationwide retrospective cohort study.BMC neurology · 2026Article
- Outcomes of Reinitiating Direct Oral Anticoagulants After Intracranial Hemorrhage: A Sequential Target Trial Emulation Study.JACC. Asia · 2025Article
- Characteristics and risk of stroke in emergency department patients with acute dizziness.Heliyon · 2024Article
- Impact of cerebral small vessel disease burden and drug level at admission on direct oral anticoagulant associated intracerebral hemorrhage.European stroke journal · 2024Article
- Differences between atrial fibrillation diagnosed before and after stroke: A large real-world cohort study.PloS one · 2024Article
- Atrial Fibrillation in Adult Congenital Heart Increase Ischemic Stroke Risk Even at Low CHAReviews in cardiovascular medicine · 2023Article
- Can markers of disease severity improve the predictive power of claims-based multimorbidity indices?Journal of the American Geriatrics Society · 2023Article
- Weekend effect on 30-day mortality for ischemic and hemorrhagic stroke analyzed using severity index and staffing level.PloS one · 2023Article
- Post-Intracranial Hemorrhage Antithrombotic Therapy in Patients With Atrial Fibrillation.Journal of the American Heart Association · 2022Article
- Analysis of Anticoagulation Therapy and Anticoagulation-Related Outcomes Among Asian Patients After Mechanical Valve Replacement.JAMA network open · 2022Article
- Utilization of screening and treatment for osteoporosis among stroke survivors.Frontiers in endocrinology · 2022Article
- Effects of long-term anti-seizure medication monotherapy on all-cause death in patients with post-stroke epilepsy: a nationwide population-based study in Taiwan.BMC neurology · 2021Article
- Dialysis Mode and Associated Outcomes in Patients With End-Stage Renal Disease and Atrial Fibrillation: A 14-Year Nationwide Cohort Study.Journal of the American Heart Association · 2021Article
- Atrial fibrillation and associated outcomes in patients with peritoneal dialysis and hemodialysis: a 14-year nationwide population-based study.Journal of nephrology · 2021Article
- Functional and Cognitive Impairments Increased Risks of Outcomes of Healthcare Utilization in Patients With Stroke Receiving Home and Community-Based Care in Taiwan.Frontiers in public health · 2021Article
- Late outcomes of endovascular aortic stent graft therapy in patients with chronic kidney disease.Medicine · 2020Observational
- Choosing and Doing wisely: triage level I resuscitation a possible new field for starting palliative care and avoiding low-value care - a nationwide matched-pair retrospective cohort study in Taiwan.BMC palliative care · 2020Article
Corrections and comments
- Erratum issued
Authors and funding
8 authors at 7 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStroke severity is an important outcome predictor for intracerebral hemorrhage (ICH) but is typically unavailable in administrative claims data. We validated a claims-based stroke severity index (SSI) in patients with ICH in Taiwan.
methodsConsecutive ICH patients from hospital-based stroke registries were linked with a nationwide claims database. Stroke severity, assessed using the National Institutes of Health Stroke Scale (NIHSS), and functional outcomes, assessed using the modified Rankin Scale (mRS), were obtained from the registries. The SSI was calculated based on billing codes in each patient's claims. We assessed two types of criterion-related validity (concurrent validity and predictive validity) by correlating the SSI with the NIHSS and the mRS. Logistic regression models with or without stroke severity as a continuous covariate were fitted to predict mortality at 3, 6, and 12 months.
resultsThe concurrent validity of the SSI was established by its significant correlation with the admission NIHSS (r = 0.731; 95% confidence interval [CI], 0.705-0.755), and the predictive validity was verified by its significant correlations with the 3-month (r = 0.696; 95% CI, 0.665-0.724), 6-month (r = 0.685; 95% CI, 0.653-0.715) and 1-year (r = 0.664; 95% CI, 0.622-0.702) mRS. Mortality models with NIHSS had the highest area under the receiver operating characteristic curve, followed by models with SSI and models without any marker of stroke severity.
conclusionsThe SSI appears to be a valid proxy for the NIHSS and an effective adjustment for stroke severity in studies of ICH outcome with administrative claims data.
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