Evidence map›Paper›PMID 28135005›Full record

ReviewComprehensive Physiology2016

Dendritic Release of Neurotransmitters.

Mike Ludwig, David Apps, John Menzies, Jyoti C Patel, Margaret E Rice

Open access · greenAbstract readReview
In one paragraph

Review in Comprehensive Physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 61 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. The Inhibition of TREK-1 KInternational journal of molecular sciences · 2024
    Article
  8. Article
  9. Article
  10. Synaptotagmin-1 is a CaCell reports · 2023
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. The neuropeptide landscape of human prefrontal cortex.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Mike LudwigCentre for Integrative Physiology, University of Edinburgh, Edinburgh, United Kingdom.
David AppsCentre for Integrative Physiology, University of Edinburgh, Edinburgh, United Kingdom.
John MenziesCentre for Integrative Physiology, University of Edinburgh, Edinburgh, United Kingdom.
Jyoti C PatelDepartment of Neurosurgery, New York University School of Medicine, New York, USA.
Margaret E RiceDepartment of Neurosurgery, New York University School of Medicine, New York, USA.
University of Edinburgh · GBNew York University · US

Funding

Diet, Insulin, Dopamine, and Reward.R01DA033811 · NIDA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CARR, KENNETH D, REITH, MAARTEN E · 2012 to 2016
$2.8M
Dopamine Release Regulation by Co-Released Glutamate and GABAR01DA038616 · NIDA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI RICE, MARGARET E · 2015 to 2019
$2.0M
Development of protein molecular probes for detection of alpha synuclein oligomeric assembliesR21AG049137 · NIA · NEW YORK UNIVERSITY · PI KIM, JIN RYOUN · 2015 to 2016
$392k
Biotechnology and Biological Sciences Research Council BB/J004723/1Medical Research Council MR/M022838/1NIA NIH HHS R21 AG049137NIDA NIH HHS R01 DA033811NIDA NIH HHS R01 DA038616
6 · The paper itself

Abstract

Release of neuroactive substances by exocytosis from dendrites is surprisingly widespread and is not confined to a particular class of transmitters: it occurs in multiple brain regions, and includes a range of neuropeptides, classical neurotransmitters, and signaling molecules, such as nitric oxide, carbon monoxide, ATP, and arachidonic acid. This review is focused on hypothalamic neuroendocrine cells that release vasopressin and oxytocin and midbrain neurons that release dopamine. For these two model systems, the stimuli, mechanisms, and physiological functions of dendritic release have been explored in greater detail than is yet available for other neurons and neuroactive substances. © 2017 American Physiological Society. Compr Physiol 7:235-252, 2017.

Indexed as

AnimalsBrainCalciumDendritesDopamineExocytosisNeurotransmitter AgentsOxytocinVasopressinsCalciumDopamineNeurotransmitter AgentsOxytocinVasopressins

Identifiers

PMID28135005
PMCPMC5381730
OpenAlexW2566352151

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.