ArticleHistopathology2017
Lanthanum deposition from oral lanthanum carbonate in the upper gastrointestinal tract.
Article in Histopathology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The trial behind it
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Who cites it
19 citing papers in PubMed, 43 citations in OpenAlex.
- Lanthanum Carbonate Nanosheets Based Colloidal Hydrogel for Modulating Innate & Adaptive Tumor Immunotherapy by Augmented Cellular Pyroptosis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Gastric Lanthanum Deposition in Advanced CKD: An Underrecognized Diagnostic Pitfall in Refractory Anemia and Mucosal Injury.International journal of nephrology · 2026Review
- Crystal-Storing Histiocytosis of the Duodenum in a Patient With IgG-Lambda Multiple Myeloma.International journal of surgical pathology · 2025Article
- A Case of Intestinal Granular Calcifications Associated With Phosphate Binder Use in a Patient on Hemodialysis.Clinical case reports · 2025Article
- Drug-induced mucosal alterations observed during esophagogastroduodenoscopy.World journal of gastroenterology · 2024Review
- The deposition of lanthanum carbonate may activate macrophages to induce gastrointestinal mucosal injury in patients with chronic kidney disease: an in vitro caco-2/THP-1 macrophage coculture model study.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2024Article
- Lanthanum Gastropathy in Gastrectomy Specimen: A Case Report.Gastro hep advances · 2024Article
- Article
- Gastric lanthanosis (lanthanum deposition) in an immunosuppressed patient that discontinued lanthanum carbonate seven years ago.Clinical case reports · 2021Article
- [Unexpected deposits in the upper gastrointestinal tract : When medical history matters].Der Pathologe · 2021Article
- Review
- Phosphate binders in chronic kidney disease: an updated narrative review of recent data.Journal of nephrology · 2020Review
- Distribution of lanthanum carbonate in the gastric mucosa confirmed by electron microscopy with a magnified endoscopy: a case report and literature review.Clinical journal of gastroenterology · 2020Review
- Review of the diagnosis of gastrointestinal lanthanum deposition.World journal of gastroenterology · 2020Review
- Clinical Evaluation of the Safety, Efficacy and Tolerability of Lanthanum Carbonate in the Management of Hyperphosphatemia in Patients with End-Stage Renal Disease.Therapeutics and clinical risk management · 2020Review
- Utility of Scanning Electron Microscopy Elemental Analysis Using the 'NanoSuit' Correlative Light and Electron Microscopy Method in the Diagnosis of Lanthanum Phosphate Deposition in the Esophagogastroduodenal Mucosa.Diagnostics (Basel, Switzerland) · 2019Article
- Frequent Involvement of the Duodenum with Lanthanum Deposition: A Retrospective Observational Study.Internal medicine (Tokyo, Japan) · 2019Observational
- Lanthanum Deposition in the Stomach in the Absence of Helicobacter pylori Infection.Internal medicine (Tokyo, Japan) · 2018Article
- Long-Term Mortality and Bone Safety in Patients with End-Stage Renal Disease Receiving Lanthanum Carbonate.Nephron · 2018Observational
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
aimsLanthanum carbonate is used as an alternative to calcium-based phosphate binders to manage hyperphosphataemia in patients with renal failure. The deposition of lanthanum within gastroduodenal mucosa of patients treated with the medication has been described, but given the relative novelty of this entity, the histiocytic deposits in the gastroduodenal mucosa can be confused with a variety of other processes, including infections and other drug-induced forms of injury. METHODS AND
resultsWe describe five cases of lanthanum phosphate deposition in upper gastrointestinal (GI) tract biopsies. Three cases were confirmed with scanning electron microscopy and energy dispersive X-ray analysis, including one unique patient, status post-renal transplant for polycystic kidney disease, who had last taken lanthanum 7 years prior to biopsy.
conclusionLanthanum deposition in the upper GI tract is a mimic of other drug-related forms of GI injury, including iron pill-related gastropathy. The key to making this diagnosis is a thorough drug history and awareness of the histological features.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.