Evidence map›Paper›PMID 28134920›Full record

Trial reportBone marrow transplantation2017

Lymphocyte expansion after unrelated cord blood allogeneic stem cell transplantation in adults.

Y Le Bris, T Guillaume, A Ménard, M Illiaquer, J Martin, S Malard, A Duquesne, P Peterlin, C Debord, N Robillard and 8 more

Open access · bronzeAbstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in Bone marrow transplantation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 4 institutions in 1 country.

Y Le BrisHematology Biology, University Hospital, Nantes, France.
T GuillaumeDepartment of Hematology, University Hospital, Nantes, France.
A MénardHematology Biology, University Hospital, Nantes, France.
M IlliaquerVirology, University Hospital, Nantes, France.
J MartinImmunology, University Hospital, Nantes, France.
S MalardEtablissement Français du Sang, Nantes, France.
A DuquesneEtablissement Français du Sang, Nantes, France.
P PeterlinDepartment of Hematology, University Hospital, Nantes, France.
C DebordHematology Biology, University Hospital, Nantes, France.
N RobillardHematology Biology, University Hospital, Nantes, France.
M EveillardHematology Biology, University Hospital, Nantes, France.
S WuillèmeHematology Biology, University Hospital, Nantes, France.
J DelaunayDepartment of Hematology, University Hospital, Nantes, France.
M MohtyHôpital Saint-Antoine, Paris University UPMC, INSERM U938, Paris, France.
A GarnierDepartment of Hematology, University Hospital, Nantes, France.
P MoreauDepartment of Hematology, University Hospital, Nantes, France.
M C BénéHematology Biology, University Hospital, Nantes, France.
P ChevallierDepartment of Hematology, University Hospital, Nantes, France.
Centre Hospitalier Universitaire de Nantes · FRÉtablissement Français du Sang · FRInserm · FRNantes Université · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Limited information is available regarding the incidence and features of lymphocyte expansions after allogeneic hematopoietic stem cell transplantation (allo-HSCT). Large granular lymphocytes (LGL) expansions have been reported after bone marrow or peripheral blood, but not after unrelated cord blood (UCB) allo-HSCT, associated with indolent clinical courses and favorable outcomes. Here, we considered 85 recipients of UCB allo-HSCT to more broadly define the impact of lymphocytosis, not limited to LGL. Sustained lymphocytosis was observed in 21 (25%) patients at a median onset of 12.6 months and with a median duration of 12 months. Immunophenotypic analysis showed predominantly CD8

Indexed as

Cord Blood Stem Cell TransplantationHematopoietic Stem Cell TransplantationAdultAgedAllograftsB-LymphocytesCD8-Positive T-LymphocytesDisease-Free SurvivalFollow-Up StudiesHematologic NeoplasmsHumansMaleMiddle AgedSurvival Rate

Identifiers

PMID28134920
OpenAlexW2581238306

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.