Evidence map›Paper›PMID 28134915›Full record

ArticleNature microbiology2017

Structural basis for antibody cross-neutralization of respiratory syncytial virus and human metapneumovirus.

Xiaolin Wen, Jarrod J Mousa, John T Bates, Robert A Lamb, James E Crowe, Theodore S Jardetzky

Open access · greenAbstract read
In one paragraph

Article in Nature microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

77 citing papers in PubMed, 91 citations in OpenAlex.

  1. Trial
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  12. Estimated Vaccine Effectiveness for Respiratory Syncytial Virus-Related Acute Respiratory Illness in Older Adults: Findings From the First Postlicensure Season.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Article
  13. Article
  14. Article
  15. Genomic surveillance of human metapneumovirus in the United States, 2010 - 2025.medRxiv : the preprint server for health sciences · 2026
    Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review

17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Xiaolin WenDepartment of Structural Biology, Stanford University School of Medicine, Stanford, California 94305, USA.
Jarrod J MousaVanderbilt Vaccine Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA.
John T BatesVanderbilt Vaccine Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA.ORCID http://orcid.org/0000-0001-5545-6871
Robert A LambHoward Hughes Medical Institute, Northwestern University, Evanston, Illinois 60208-3500, USA.
James E CroweVanderbilt Vaccine Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA.
Theodore S JardetzkyDepartment of Structural Biology, Stanford University School of Medicine, Stanford, California 94305, USA.
Vanderbilt University · USStanford University · USNorthwestern University · US

Funding

Vanderbilt Infection Pathogenesis and Epidemiology Research Training ProgramT32AI007474 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI KALAMS, SPYROS A · 1995 to 2025
$6.9M
STRUCTURAL STUDIES OF PARAMYXOVIRUS FUSION PROTEINSR01GM061050 · NIGMS · STANFORD UNIVERSITY · PI JARDETZKY, THEODORE S · 2000 to 2015
$3.1M
STRUCTURE &EXPRESSION OF THE PARAMYXOVIRUS SV5 GENOMER01AI023173 · NIAID · NORTHWESTERN UNIVERSITY · PI LAMB, ROBERT A · 1986 to 2010
$3.1M
NIAID NIH HHS R01 AI023173NIAID NIH HHS T32 AI007474NIGMS NIH HHS R01 GM061050
6 · The paper itself

Abstract

Respiratory syncytial virus (RSV) and human metapneumovirus (HMPV) are two closely related viruses that cause bronchiolitis and pneumonia in infants and the elderly

Indexed as

Cross ReactionsAntibodies, MonoclonalAntibodies, NeutralizingAntibodies, ViralCrystallography, X-RayMetapneumovirusModels, MolecularProtein BindingProtein ConformationRespiratory Syncytial VirusesViral Fusion ProteinsAntibodies, MonoclonalAntibodies, NeutralizingAntibodies, ViralViral Fusion Proteins

Identifiers

PMID28134915
PMCPMC5308794
OpenAlexW2580797815

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.