Evidence map›Paper›PMID 28134816›Full record

ArticleInternational journal of molecular sciences2017

α6 Integrin (α6

Elodie Metral, Nicolas Bechetoille, Frédéric Demarne, Walid Rachidi, Odile Damour

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. SMOC1 and IL-4 and IL-13 Cytokines Interfere with CaThe Journal of investigative dermatology · 2021
    Article
  5. Article
  6. Article
  7. Review
  8. Production of progenitor cells from primary human epithelial cell monolayer cultures.In vitro cellular & developmental biology. Animal · 2018
    Article
  9. Extracellular Matrix as a Regulator of Epidermal Stem Cell Fate.International journal of molecular sciences · 2018
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Elodie MetralGattefossé, 36 chemin de Genas, F-69800 Saint-Priest, France. odile.damour@chu-lyon.fr.
Nicolas BechetoilleGattefossé, 36 chemin de Genas, F-69800 Saint-Priest, France. nbechetoille@gattefosse.com.
Frédéric DemarneGattefossé, 36 chemin de Genas, F-69800 Saint-Priest, France. fdemarne@gattefosse.com.
Walid RachidiCommissariat à l'énergie atomique et aux énergies alternatives (CEA)/Institut Nanosciences et cryogénie (INAC)/SYstèmes Moléculaires et nanoMatériaux pour l'Energie et la Santé (SyMMES)/Lésions des acides nucléiques (LAN), 17 avenue des martyrs, F-38054 Grenoble CEDEX, France. walid.rachidi@cea.fr.
Odile DamourHospices Civils de LYON (HCL)/Banque de Tissus et Cellules/Laboratoire des Substituts Cutanés, 5 place d'Arsonval, F-69000 Lyon, France. odile.damour@chu-lyon.fr.
Commissariat à l'Énergie Atomique et aux Énergies Alternatives · FRHospices Civils de Lyon · FRInstitut Nanosciences et Cryogénie · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The epidermis basal layer is composed of two keratinocyte populations: Keratinocyte Stem cells (KSC) and Transitory Amplifying (TA) cells that arise from KSC division. Unfortunately, no specific marker exists to differ between KSC and TA cells. Here, we aimed at comparing two different methods that pretended to isolate these two populations: (i) the rapid adhesion method on coated substrate and (ii) the flow cytometry method, which is based on the difference in cell surface expressions of the α6 integrin and transferrin receptor (CD71). Then, we compared different parameters that are known to discriminate KSC and TA populations. Interestingly, we showed that both methods allow enrichment in stem cells. However, cell sorting by flow cytometry (α6

Indexed as

Epidermal CellsAntigens, CDCell AdhesionCell SeparationClone CellsCollagen Type IColony-Forming Units AssayFlow CytometryHumansIntegrin alpha6KeratinocytesPhenotypeReceptors, TransferrinRegenerationStem CellsTemperatureAntigens, CDCD71 antigenCollagen Type IIntegrin alpha6Receptors, Transferrinadhesionbasal keratinocytesCD71epidermiskeratinocyte stem cellsskinα6 integrin

Identifiers

PMID28134816
PMCPMC5343818
OpenAlexW2580299152

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.