Evidence map›Paper›PMID 28134801›Full record

ReviewMarine drugs2017

Marine Antifreeze Proteins: Structure, Function, and Application to Cryopreservation as a Potential Cryoprotectant.

Hak Jun Kim, Jun Hyuck Lee, Young Baek Hur, Chang Woo Lee, Sun-Ha Park, Bon-Won Koo

Open access · goldAbstract readReview
In one paragraph

Review in Marine drugs, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
13.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 185 citations in OpenAlex.

  1. Trial
  2. Review
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  4. Cryopreservation of biological materials: applications and economic perspectives.In vitro cellular & developmental biology. Animal · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Hak Jun KimDepartment of Chemistry, Pukyong National University, Busan 48513, Korea. kimhj@pknu.ac.kr.
Jun Hyuck LeeUnit of Polar Genomics, Korea Polar Research Institute, Incheon 21990, Korea. junhyucklee@kopri.re.kr.
Young Baek HurTidal Flat Research Institute, National Fisheries Research and Development Institute, Gunsan, Jeonbuk 54014, Korea. hur0100@korea.kr.
Chang Woo LeeUnit of Polar Genomics, Korea Polar Research Institute, Incheon 21990, Korea. justay@kopri.re.kr.
Sun-Ha ParkUnit of Polar Genomics, Korea Polar Research Institute, Incheon 21990, Korea. psh@kopri.re.kr.
Bon-Won KooDepartment of Chemistry, Pukyong National University, Busan 48513, Korea. 89guti14@gmail.com.
Korea Polar Research Institute · KRPukyong National University · KRNational Institute of Fisheries Science · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antifreeze proteins (AFPs) are biological antifreezes with unique properties, including thermal hysteresis(TH),ice recrystallization inhibition(IRI),and interaction with membranes and/or membrane proteins. These properties have been utilized in the preservation of biological samples at low temperatures. Here, we review the structure and function of marine-derived AFPs, including moderately active fish AFPs and hyperactive polar AFPs. We also survey previous and current reports of cryopreservation using AFPs. Cryopreserved biological samples are relatively diverse ranging from diatoms and reproductive cells to embryos and organs. Cryopreserved biological samples mainly originate from mammals. Most cryopreservation trials using marine-derived AFPs have demonstrated that addition of AFPs can improve post-thaw viability regardless of freezing method (slow-freezing or vitrification), storage temperature, and types of biological sample type.

Indexed as

AnimalsAntifreeze ProteinsAquatic OrganismsCryopreservationCryoprotective AgentsCrystallizationFreezingIceTemperatureAntifreeze ProteinsCryoprotective AgentsIceantifreeze proteinscryoprotectantice-binding proteinsice recrystallization inhibitionslow-freezingvitrification

Identifiers

PMID28134801
PMCPMC5334608
OpenAlexW2581613943

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.