Evidence map›Paper›PMID 28134770›Full record

ReviewInternational journal of molecular sciences2017

Review: Receptor Targeted Nuclear Imaging of Breast Cancer.

Simone U Dalm, John Fred Verzijlbergen, Marion De Jong

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.2field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 33 citations in OpenAlex.

  1. Review
  2. The preclinical study ofAnnals of nuclear medicine · 2023
    Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Fluorine-18 Labeled Fluorofuranylnorprogesterone ([Molecules (Basel, Switzerland) · 2019
    Article
  11. Article
  12. Theranostics · 2018
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Simone U DalmDepartment of Radiology & Nuclear medicine, Erasmus MC, Wytemaweg 80, 3015CN Rotterdam, The Netherlands. s.dalm@erasmusmc.nl.
John Fred VerzijlbergenDepartment of Radiology & Nuclear medicine, Erasmus MC, Wytemaweg 80, 3015CN Rotterdam, The Netherlands. j.verzijlbergen@erasmusmc.nl.
Marion De JongDepartment of Radiology & Nuclear medicine, Erasmus MC, Wytemaweg 80, 3015CN Rotterdam, The Netherlands. m.hendriks-dejong@erasmusmc.nl.
Erasmus MC · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Receptor targeted nuclear imaging directed against molecular markers overexpressed on breast cancer (BC) cells offers a sensitive and specific method for BC imaging. Currently, a few targets such as estrogen receptor (ER), progesterone receptor (PR), human epidermal growth factor receptor 2 (HER2), somatostatin receptor (SSTR), and the gastrin releasing peptide receptor (GRPR) are being investigated for this purpose. Expression of these targets is BC subtype dependent and information that can be gained from lesion visualization is dependent on the target; ER-targeting radiotracers, e.g., can be used to monitor response to anti-estrogen treatment. Here we give an overview of the studies currently under investigation for receptor targeted nuclear imaging of BC. Main findings of imaging studies are summarized and (potential) purposes of lesion visualization by targeting these molecular markers are discussed. Since BC is a very heterogeneous disease and molecular target expression can vary per subtype, but also during disease progression or under influence of treatment, radiotracers for selected imaging purposes should be chosen carefully.

Indexed as

Diagnostic ImagingBreast NeoplasmsFemaleHumansMolecular Targeted TherapyReceptors, Cell SurfaceReceptors, Cell Surfacebreast cancerERGRPRHER2PETPRreceptor targeted nuclear imagingSPECTSSTR

Identifiers

PMID28134770
PMCPMC5343796
OpenAlexW2580815174

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.