Evidence map›Paper›PMID 28134751›Full record

ArticleToxins2017

Efficacy of Urtoxazumab (TMA-15 Humanized Monoclonal Antibody Specific for Shiga Toxin 2) Against Post-Diarrheal Neurological Sequelae Caused by Escherichia coli O157:H7 Infection in the Neonatal Gnotobiotic Piglet Model.

Rodney A Moxley, David H Francis, Mizuho Tamura, David B Marx, Kristina Santiago-Mateo, Mojun Zhao

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxins, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.9field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. EnterohemorrhagicInternational journal of molecular sciences · 2022
    Review
  3. Article
  4. Review
  5. Therapeutic Antibodies Against Shiga Toxins: Trends and Perspectives.Frontiers in cellular and infection microbiology · 2022
    Review
  6. Article
  7. Article
  8. Review
  9. Treatment Strategies for Infections With Shiga Toxin-ProducingFrontiers in cellular and infection microbiology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 3 countries.

Rodney A MoxleySchool of Veterinary Medicine and Biomedical Sciences, University of Nebraska-Lincoln, Lincoln, NE 68583, USA. rmoxley1@unl.edu.
David H FrancisDepartment of Veterinary and Biomedical Sciences, South Dakota State University, Brookings, SD 57007, USA. David.Francis@sdstate.edu.
Mizuho TamuraTeijin Pharma Limited, Pharmacology Research Department, 4-3-2 Asahigaoka, Hino, Tokyo 191-8512, Japan. miz.tamura@teijin.co.jp.
David B MarxDepartment of Statistics, University of Nebraska-Lincoln, Lincoln, NE 68583, USA. dmarx1@unl.edu.
Kristina Santiago-MateoCanadian Food Inspection Agency, Lethbridge Laboratory, Box 640 TWP Rd 9-1, Lethbridge, AB T1J 3Z4, Canada. Kristina.Santiago-Mateo@inspection.gc.ca.
Mojun ZhaoValley Pathologists, Inc., 1100 South Main Street, Suite 308, Dayton, OH 45409, USA. zhaomojun@gmail.com.
University of Nebraska–Lincoln · USCanadian Food Inspection Agency · CASouth Dakota State University · USTeijin (Japan) · JPUniversity Pathologists · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enterohemorrhagic

Indexed as

AnimalsAnimals, NewbornAntibodies, Monoclonal, HumanizedBrainBrain InfarctionDiarrheaDisease Models, AnimalEscherichia coli O157Germ-Free LifeHemolytic-Uremic SyndromeMeningitis, Escherichia coliNecrosisSeverity of Illness IndexShiga Toxin 2Sus scrofaTime FactorsAntibodies, Monoclonal, HumanizedShiga Toxin 2urtoxazumabenterohemorrhagic E. colignotobiotic pigletsmonoclonal antibodyShiga toxin

Identifiers

PMID28134751
PMCPMC5331429
OpenAlexW2582665266

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.