SynthesisPsychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors2017
A systematic review of the unique prospective association of negative affect symptoms and adolescent substance use controlling for externalizing symptoms.
Synthesis in Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 100 papers, 9 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
100 citing papers in PubMed, 9 syntheses or guidelines pooled it, 171 citations in OpenAlex.
- Culturally sensitive prevention programs for substance use among adolescents of color: A systematic review and meta-analysis of randomized controlled trials.Clinical psychology review · 2023Pooled it
- Effects of Brief Interventions on Internalizing Symptoms and Substance Use in Youth: A Systematic Review.Clinical child and family psychology review · 2022Pooled it
- Mental disorder and opioid overdose: a systematic review.Social psychiatry and psychiatric epidemiology · 2022Pooled it
- The Etiologic, Theory-Based, Ontogenetic Hierarchical Framework of Alcohol Use Disorder: A Translational Systematic Review of Reviews.Psychological bulletin · 2021Pooled it
- Targets for intervention to prevent substance use in young people exposed to childhood adversity: A systematic review.PloS one · 2021Pooled it
- The association between early life mental health and alcohol use behaviours in adulthood: A systematic review.PloS one · 2020Pooled it
- Associations of child and adolescent anxiety with later alcohol use and disorders: a systematic review and meta-analysis of prospective cohort studies.Addiction (Abingdon, England) · 2019Pooled it
- The daily association between affect and alcohol use: A meta-analysis of individual participant data.Psychological bulletinPooled it
- Evidence Base on Outpatient Behavioral Treatments for Adolescent Substance Use, Update 2018-2023: Current Status, Best Practices, and Opportunities for Advancing the Science.Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53Pooled it
- Predictors and moderators of marijuana and heavy alcohol use outcomes in adolescents treated for co-occurring substance use and psychiatric disorders in a randomized controlled trial.Journal of substance abuse treatment · 2021Trial
- Ultra-brief breath counting (mindfulness) training promotes recovery from stress-induced alcohol-seeking in student drinkers.Addictive behaviors · 2020Trial
- Internalizing and externalizing pathways to adolescent substance use disorders: A Multi-level analysis in Nigerian schools.Social psychiatry and psychiatric epidemiology · 2026Article
- Revisiting the role of negative affect in alcohol use disorder: A longitudinal evaluation of Koob's allostatic model.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2026Article
- Longitudinal Bidirectional Associations Between Early Adolescents' Externalizing and Posttraumatic Stress Symptoms and Substance Use Patterns.Research on child and adolescent psychopathology · 2026Article
- A Multi-Method Meta-Analysis of Neuro-Behavioral Motor Inhibition Outcomes Across Substance-Use Problems and Related Developmental Psychopathological Conditions: A Self-Regulation Approach.Clinical neuropsychiatry · 2026Article
- Distinguishing a drug use disorder from drug use in a high-risk sample of youth: A random forest classification and explanatory analysis.Drug and alcohol dependence reports · 2026Article
- Do posttreatment increases in social recovery capital mediate the relationship between lower internalizing symptoms and less substance use?Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2026Article
- Examining polygenic scores for depression, depressive symptoms from childhood to adolescence, and adolescent substance use in a diverse sample: The moderating impact of a family-centered intervention.Development and psychopathology · 2025Article
- Internalizing symptoms are indirectly associated with simultaneous alcohol and cannabis use through specific motives for simultaneous use: A longitudinal study of young adults.Alcohol, clinical & experimental research · 2025Article
- A structural equation model test of affect, family warmth, and substance use among American Indian reservation-based adolescents.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2025Article
40 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
This systematic review examines whether negative affect symptoms (i.e., anxiety, depression, and internalizing symptoms more broadly) predict subsequent adolescent substance use after controlling for co-occurring externalizing symptoms. Following PRISMA procedures, we identified 61 studies that tested the association of interest. Findings varied depending on the type of negative affect symptom and to some extent on the substance use outcome. The most consistent associations were evident for depressive symptoms, particularly as predictors of substance use composite scores. No clear association between anxiety and substance use or between internalizing symptoms and substance use was evident, and indeed these associations were as often negative as positive. Mixed findings regarding the depression-substance use association, however, also call for greater attention to potential moderating factors that may help define who, when, and in what context depression serves as an important risk factor for later substance use above and beyond risk associated with externalizing symptoms. (PsycINFO Database Record
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.