Evidence map›Paper›PMID 28134385›Full record

ArticleChemical communications (Cambridge, England)2017

Facile silicification of plastic surface for bioassays.

Seonki Hong, Ki Soo Park, Ralph Weissleder, Cesar M Castro, Hakho Lee

Open access · greenAbstract read
In one paragraph

Article in Chemical communications (Cambridge, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Seonki HongCenter for Systems Biology, Massachusetts General Hospital, Boston, MA 02114, USA. hlee@mgh.harvard.edu and Department of Radiology, Massachusetts General Hospital, Boston, MA 02114, USA.ORCID http://orcid.org/0000-0003-1440-5167
Ki Soo ParkCenter for Systems Biology, Massachusetts General Hospital, Boston, MA 02114, USA. hlee@mgh.harvard.edu and Department of Radiology, Massachusetts General Hospital, Boston, MA 02114, USA.ORCID http://orcid.org/0000-0002-0545-0970
Ralph WeisslederCenter for Systems Biology, Massachusetts General Hospital, Boston, MA 02114, USA. hlee@mgh.harvard.edu and Department of Radiology, Massachusetts General Hospital, Boston, MA 02114, USA and Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA.ORCID http://orcid.org/0000-0003-0828-4143
Cesar M CastroCenter for Systems Biology, Massachusetts General Hospital, Boston, MA 02114, USA. hlee@mgh.harvard.edu and Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA. castro.cesar@mgh.harvard.edu.ORCID http://orcid.org/0000-0002-1159-5658
Hakho LeeCenter for Systems Biology, Massachusetts General Hospital, Boston, MA 02114, USA. hlee@mgh.harvard.edu and Department of Radiology, Massachusetts General Hospital, Boston, MA 02114, USA.ORCID http://orcid.org/0000-0002-0087-0909
Massachusetts General Hospital · USHarvard University · US

Funding

Dana Farber/Harvard Cancer Consortium Career Development Program in Clinical OncologyK12CA087723 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI David Tsai Ting · 2002 to 2026
$17.9M
Novel Clickdyes for Biomedical SensingR01EB010011 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI WEISSLEDER, MD, PHD, RALPH · 2010 to 2017
$3.1M
MAGNETIC NANOSENSORS FOR BIOMEDICAL ANALYSES OF MICROVESICLESR01HL113156 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI LEE, HAKHO · 2012 to 2016
$2.1M
Multiplexed analysis of exosomes in cancer nano therapyR01CA204019 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI WEISSLEDER, MD, PHD, RALPH · 2016 to 2020
$1.9M
Analysis of scant cancer cells in fine needle aspiratesR33CA202064 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI WEISSLEDER, MD, PHD, RALPH · 2016 to 2018
$1.3M
Multiplexed exosome analyses with DNA barcodingR21CA205322 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI LEE, HAKHO · 2016 to 2017
$440k
NCI NIH HHS K12 CA087723NCI NIH HHS R01 CA204019NCI NIH HHS R21 CA205322NCI NIH HHS R33 CA202064NHLBI NIH HHS R01 HL113156NIBIB NIH HHS R01 EB010011
6 · The paper itself

Abstract

We herein report a biomimetic technique to modify plastic substrates for bioassays. The method first places a polydopamine adhesion layer to plastic surface, and then grows conformal silica coating. As proof of principle, we coated plastic microbeads to construct a disposable filter for point-of-care nucleic acid extraction.

Indexed as

BiomimeticsCell LineCoated Materials, BiocompatibleFiltrationHumansIndolesMicrospheresNucleic AcidsPlasticsPoint-of-Care SystemsPolymersSilicon DioxideSurface PropertiesCoated Materials, BiocompatibleIndolesNucleic AcidsPlasticspolydopaminePolymersSilicon Dioxide

Identifiers

PMID28134385
PMCPMC5327824
OpenAlexW2582722567

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.