Evidence map›Paper›PMID 28134293›Full record

ArticleScientific reports2017

Ultra-fast cell counters based on microtubular waveguides.

Cornelius S Bausch, Christian Heyn, Wolfgang Hansen, Insa M A Wolf, Björn-Philipp Diercks, Andreas H Guse, Robert H Blick

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Cornelius S BauschInstitute of Nanostructure and Solid State Physics, University of Hamburg, Jungiusstraße 11c, Hamburg, Germany.
Christian HeynInstitute of Nanostructure and Solid State Physics, University of Hamburg, Jungiusstraße 11c, Hamburg, Germany.
Wolfgang HansenInstitute of Nanostructure and Solid State Physics, University of Hamburg, Jungiusstraße 11c, Hamburg, Germany.
Insa M A WolfCalcium Signaling Group, Department of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, Martinistraße 52, Hamburg, Germany.
Björn-Philipp DiercksCalcium Signaling Group, Department of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, Martinistraße 52, Hamburg, Germany.
Andreas H GuseCalcium Signaling Group, Department of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, Martinistraße 52, Hamburg, Germany.
Robert H BlickInstitute of Nanostructure and Solid State Physics, University of Hamburg, Jungiusstraße 11c, Hamburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present a radio-frequency impedance-based biosensor embedded inside a semiconductor microtube for the in-flow detection of single cells. An impedance-matched tank circuit and a tight wrapping of the electrodes around the sensing region, which creates a close, leakage current-free contact between cells and electrodes, yields a high signal-to-noise ratio. We experimentally show a twofold improved sensitivity of our three-dimensional electrode structure to conventional planar electrodes and support these findings by finite element simulations. Finally, we report on the differentiation of polystyrene beads, primary mouse T lymphocytes and Jurkat T lymphocytes using our device.

Indexed as

Biosensing TechniquesElectric ImpedanceFlow CytometrySemiconductorsHumansModels, TheoreticalT-Lymphocytes

Identifiers

PMID28134293
PMCPMC5278506

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.