ArticleScientific reports2017
Does von Willebrand factor improve the predictive ability of current risk stratification scores in patients with atrial fibrillation?
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Comprehensive comparison of stroke risk score performance: a systematic review and meta-analysis among 6 267 728 patients with atrial fibrillation.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2022Pooled it
- Prognostic value of von Willebrand factor in patients with atrial fibrillation: A meta-analysis.Medicine · 2018Pooled it
- Cardiovascular burden of long coronavirus disease: Clinical challenges and emerging biomarkers.World journal of cardiology · 2026Review
- Cross-Sectional Analysis of Sleep Quality and Vascular Health in Shift- and Day-Working Nurses.Clocks & sleep · 2025Article
- Biomarkers of increased bleeding risk in patients with atrial fibrillation on oral anticoagulation: a narrative review.Cardiovascular diagnosis and therapy · 2025Review
- Routinely available inflammation biomarkers to predict stroke and mortality in atrial fibrillation.Clinics (Sao Paulo, Brazil) · 2025Article
- The Association between Coagulation and Atrial Fibrillation.Biomedicines · 2024Review
- Stroke in Atrial Fibrillation and Other Atrial Dysrhythmias.Current cardiology reports · 2023Review
- Soluble P-Selectin and von Willebrand Factor Rise in Healthy Volunteers Following Non-exertional Ascent to High Altitude.Frontiers in physiology · 2022Article
- A nomogram for determining the disease-specific survival in invasive lobular carcinoma of the breast: A population study.Medicine · 2020Article
- Predictive Nomogram for Midterm to Long-Term Prognosis in Patients with Papillary Renal Cell Carcinoma Based on Data from the Surveillance, Epidemiology, and End Results (SEER) Program.Medical science monitor : international medical journal of experimental and clinical research · 2020Article
- Association of NT-proBNP and GDF-15 with markers of a prothrombotic state in patients with atrial fibrillation off anticoagulation.Clinical research in cardiology : official journal of the German Cardiac Society · 2020Article
- Development and validation of a nomogram containing the prognostic determinants of chondrosarcoma based on the Surveillance, Epidemiology, and End Results database.International journal of clinical oncology · 2019Article
- A nomogram for determining the disease-specific survival in Ewing sarcoma: a population study.BMC cancer · 2019Article
- Development and validation of a nomogram for osteosarcoma-specific survival: A population-based study.Medicine · 2019Article
- Risk factors of thromboembolism in nonvalvular atrial fibrillation patients with low CHA2DS2-VASc score.Medicine · 2019Observational
- Soluble Fibrin Monomer Complex and Prediction of Cardiovascular Events in Atrial Fibrillation: The Observational Murcia Atrial Fibrillation Project.Journal of general internal medicine · 2018Observational
- Long-Term Stroke Risk Prediction in Patients With Atrial Fibrillation: Comparison of the ABC-Stroke and CHAJournal of the American Heart Association · 2017Article
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Von Willebrand factor (vWF) is a biomarker of endothelial dysfunction. We investigated its role on prognosis in anticoagulated atrial fibrillation (AF) patients and determined whether its addition to clinical risk stratification schemes improved event-risk prediction. Consecutive outpatients with non-valvular AF were recruited and rates of thrombotic/cardiovascular events, major bleeding and mortality were recorded. The effect of vWF on prognosis was calculated using a Cox regression model. Improvements in predictive accuracy over current scores were determined by calculating the integrated discrimination improvement (IDI), net reclassification improvement (NRI), comparison of receiver-operator characteristic (ROC) curves and Decision Curve Analysis (DCA). 1215 patients (49% males, age 76 (71-81) years) were included. Follow-up was almost 7 years. Significant associations were found between vWF and cardiovascular events, stroke, mortality and bleeding. Based on IDI and NRI, addition of vWF to CHA
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