Evidence map›Paper›PMID 28133617›Full record

ArticleJournal of diabetes research2017

Molecular Analysis of a Genetic Variants Panel Related to Nutrients and Metabolism: Association with Susceptibility to Gestational Diabetes and Cardiometabolic Risk in Affected Women.

Marica Franzago, Federica Fraticelli, Antonio Nicolucci, Claudio Celentano, Marco Liberati, Liborio Stuppia, Ester Vitacolonna

Abstract read
In one paragraph

Article in Journal of diabetes research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Marica FranzagoLaboratory of Molecular Genetics, Department of Psychological, Health and Territorial Sciences, School of Medicine and Health Sciences, "G. d'Annunzio" University, Chieti-Pescara, Via dei Vestini 31, 66013 Chieti, Italy; Ce.S.I-Met, "G. d'Annunzio" University, Chieti-Pescara, Via Colle dell'Ara No. 1, 66100 Chieti, Italy.ORCID 0000-0002-4830-8034
Federica FraticelliCe.S.I-Met, "G. d'Annunzio" University, Chieti-Pescara, Via Colle dell'Ara No. 1, 66100 Chieti, Italy; Department of Medicine and Aging, School of Medicine and Health Sciences, "G. d'Annunzio" University, Chieti-Pescara, Chieti, Italy.ORCID 0000-0002-8169-1864
Antonio NicolucciCenter for Outcomes Research and Clinical Epidemiology (CORE), Pescara, Italy.
Claudio CelentanoDepartment of Medicine and Aging, School of Medicine and Health Sciences, "G. d'Annunzio" University, Chieti-Pescara, Chieti, Italy.
Marco LiberatiDepartment of Medicine and Aging, School of Medicine and Health Sciences, "G. d'Annunzio" University, Chieti-Pescara, Chieti, Italy.
Liborio StuppiaLaboratory of Molecular Genetics, Department of Psychological, Health and Territorial Sciences, School of Medicine and Health Sciences, "G. d'Annunzio" University, Chieti-Pescara, Via dei Vestini 31, 66013 Chieti, Italy; Ce.S.I-Met, "G. d'Annunzio" University, Chieti-Pescara, Via Colle dell'Ara No. 1, 66100 Chieti, Italy.
Ester VitacolonnaCe.S.I-Met, "G. d'Annunzio" University, Chieti-Pescara, Via Colle dell'Ara No. 1, 66100 Chieti, Italy; Department of Medicine and Aging, School of Medicine and Health Sciences, "G. d'Annunzio" University, Chieti-Pescara, Chieti, Italy.ORCID 0000-0003-1756-661X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gestational diabetes mellitus (GDM) is the most frequent metabolic disorder in pregnancy. Women with a GDM history are at increased risk of developing diabetes and cardiovascular diseases. Studies have demonstrated a significant correlation between several genes involved in the metabolic pathway of insulin and environmental factors. The aim of this study was to investigate the relationship between clinical parameters in GDM and variants in genes involved with nutrients and metabolism. Several variants

Indexed as

Genetic Predisposition to DiseaseGenotypePolymorphism, Single NucleotideAdultAlpha-Ketoglutarate-Dependent Dioxygenase FTOApolipoprotein A-VDiabetes, GestationalFemaleGene FrequencyGenetic Association StudiesHumansPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaPPAR gammaPregnancyReceptor, Melanocortin, Type 4Receptors, LDLAlpha-Ketoglutarate-Dependent Dioxygenase FTOApolipoprotein A-VFTO protein, humanPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaPPAR gammaReceptor, Melanocortin, Type 4Receptors, LDLTCF7L2 protein, humanTranscription Factor 7-Like 2 Protein

Identifiers

PMID28133617
PMCPMC5241477

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.