Evidence map›Paper›PMID 28133589›Full record

ArticleCurrent epidemiology reports2016

Dependent Happenings: A Recent Methodological Review.

M Elizabeth Halloran, Michael G Hudgens

Abstract read
In one paragraph

Article in Current epidemiology reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Trial
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  4. Institutional spillover effects of antimicrobial use on antimicrobial resistance andAntimicrobial stewardship & healthcare epidemiology : ASHE · 2026
    Article
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  20. Dynamical Modeling as a Tool for Inferring Causation.American journal of epidemiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

M Elizabeth HalloranCenter for Inference and Dynamics of Infectious Diseases, Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center; Department of Biostatistics, School of Public Health, University of Washington.
Michael G HudgensDepartment of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill.

Funding

Methods for Evaluating Vaccine EfficacyR37AI032042 · NIAID · FRED HUTCHINSON CANCER RESEARCH CENTER · PI HALLORAN, M ELIZABETH · 2010 to 2019
$5.1M
Causal Inference in Infectious Disease Prevention StudiesR01AI085073 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HUDGENS, MICHAEL G · 2010 to 2024
$4.5M
Causal Inference in Infectious Disease Prevention StudiesR37AI085073 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Michael G Hudgens · 2026 to 2026
$394k
NIAID NIH HHS R01 AI085073NIAID NIH HHS R37 AI032042NIAID NIH HHS R37 AI085073
6 · The paper itself

Abstract

One hundred years ago Sir Ronald Ross published his treatise on a general Theory of Happenings. Dependent happenings are those in which the frequency depends on the number already affected. When there is dependency of events, interventions can have different types of effects. Interventions such as vaccination can have direct protective effects for the person receiving the treatment, as well as indirect/spillover effects for others in the population. Causal inference is a framework for carefully defining the causal effect of a treatment, exposure, or policy, and then determining conditions under which such effects can be estimated from the observed data. We consider here scenarios in which the potential outcomes of an individual can depend on the treatment of other individuals in the population, known as causal inference with interference. Much of the research so far has assumed the population is divided into groups or clusters, and individuals can interfere with others within their clusters but not across clusters. Recent developments have assumed more general forms of interference. We review some of the different types of effects that have been defined for dependent happenings, particularly using the methods of causal inference with interference. Many of the methods are applicable across disciplines, such as infectious diseases, social sciences, and economics.

Indexed as

causal inferencecounterfactualdependent happeningsexperimental designherd immunityindirect effectsnetworkspeer influence effectspotential outcomespillover effectsSUTVA

Identifiers

PMID28133589
PMCPMC5267358

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.