Evidence map›Paper›PMID 28133541›Full record

ArticleMicrobial genomics2016

Putatively novel serotypes and the potential for reduced vaccine effectiveness: capsular locus diversity revealed among 5405 pneumococcal genomes.

Andries J van Tonder, James E Bray, Sigríður J Quirk, Gunnsteinn Haraldsson, Keith A Jolley, Martin C J Maiden, Steen Hoffmann, Stephen D Bentley, Ásgeir Haraldsson, Helga Erlendsdóttir and 2 more

Abstract read
In one paragraph

Article in Microbial genomics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
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  5. Article
  6. Microbiology spectrum · 2024
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  10. Carbon Source-Dependent Changes of the Structure ofInternational journal of molecular sciences · 2021
    Article
  11. VPsero: Rapid Serotyping ofFrontiers in microbiology · 2021
    Article
  12. Serotype Distribution ofInfection and drug resistance · 2021
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Andries J van Tonder1​Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
James E Bray2​Department of Zoology, University of Oxford, Oxford, United Kingdom.
Sigríður J Quirk3​Clinical Microbiology, University of Iceland and Landspitali University Hospital, Reykjavik, Iceland.
Gunnsteinn Haraldsson3​Clinical Microbiology, University of Iceland and Landspitali University Hospital, Reykjavik, Iceland.
Keith A Jolley2​Department of Zoology, University of Oxford, Oxford, United Kingdom.
Martin C J Maiden2​Department of Zoology, University of Oxford, Oxford, United Kingdom.
Steen Hoffmann4​Department of Microbiology and Infection Control, Statens Serum Institut, Copenhagen, Denmark.
Stephen D Bentley5​Pathogen Genomics, Wellcome Trust Sanger Institute, Hinxton, United Kingdom.
Ásgeir Haraldsson3​Clinical Microbiology, University of Iceland and Landspitali University Hospital, Reykjavik, Iceland.
Helga Erlendsdóttir3​Clinical Microbiology, University of Iceland and Landspitali University Hospital, Reykjavik, Iceland.
Karl G Kristinsson3​Clinical Microbiology, University of Iceland and Landspitali University Hospital, Reykjavik, Iceland.
Angela B Brueggemann1​Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.

Funding

Wellcome Trust 04992/Z/14/ZWellcome Trust 083511Wellcome Trust 098051
6 · The paper itself

Abstract

The pneumococcus is a leading global pathogen and a key virulence factor possessed by the majority of pneumococci is an antigenic polysaccharide capsule ('serotype'), which is encoded by the capsular (

Indexed as

Genetic VariationPneumococcal VaccinesBacterial CapsulesHumansPneumococcal InfectionsPolysaccharides, BacterialSerotypingStreptococcus pneumoniaePneumococcal VaccinesPolysaccharides, Bacterialmolecular epidemiologypneumococcal capsular locussequence-based serotypingvaccine impact

Identifiers

PMID28133541
PMCPMC5266551

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.