Variability in local action potential durations, dispersion of repolarization and wavelength restitution in aged wild-type and Scn5a

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

1. Restitution metrics in Brugada syndrome: a systematic review and meta-analysis.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2020
   Pooled it
2. Measures of repolarization variability predict ventricular arrhythmogenesis in heptanol-treated Langendorff-perfused mouse hearts.Current research in physiology · 2021
   Article
3. Brugada syndrome: A comprehensive review of pathophysiological mechanisms and risk stratification strategies.International journal of cardiology. Heart & vasculature · 2020
   Review
4. Effects of granulocyte colony‑stimulating factor on rabbit carotid and porcine heart models of chronic obliterative arterial disease.Molecular medicine reports · 2019
   Article
5. Higher Dispersion Measures of Conduction and Repolarization in Type 1 Compared to Non-type 1 Brugada Syndrome Patients: An Electrocardiographic Study From a Single Center.Frontiers in cardiovascular medicine · 2018
   Article
6. Spontaneous type 1 pattern, ventricular arrhythmias and sudden cardiac death in Brugada Syndrome: an updated systematic review and meta-analysis.Journal of geriatric cardiology : JGC · 2017
   Article
7. Electrophysiological mechanisms of long and short QT syndromes.International journal of cardiology. Heart & vasculature · 2017
   Review
8. The role of gap junctions in inflammatory and neoplastic disorders (Review).International journal of molecular medicine · 2017
   Review
9. Tachycardia-bradycardia syndrome: Electrophysiological mechanisms and future therapeutic approaches (Review).International journal of molecular medicine · 2017
   Review
10. Animal models of atherosclerosis.Biomedical reports · 2017
    Article
11. Mouse models of atherosclerosis: a historical perspective and recent advances.Lipids in health and disease · 2017
    Review
12. Animal models for the study of primary and secondary hypertension in humans.Biomedical reports · 2016
    Article
13. Gap junction inhibition by heptanol increases ventricular arrhythmogenicity by reducing conduction velocity without affecting repolarization properties or myocardial refractoriness in Langendorff-perfused mouse hearts.Molecular medicine reports · 2016
    Article
14. Anti-arrhythmic effects of hypercalcemia in hyperkalemic, Langendorff-perfused mouse hearts.Biomedical reports · 2016
    Article
15. What Is the Arrhythmic Substrate in Viral Myocarditis? Insights from Clinical and Animal Studies.Frontiers in physiology · 2016
    Review
16. Electrophysiological Mechanisms of Brugada Syndrome: Insights from Pre-clinical and Clinical Studies.Frontiers in physiology · 2016
    Review

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

4 authors at 2 institutions in 2 countries.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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