Evidence map›Paper›PMID 28132899›Full record

ArticleBiochimica et biophysica acta. Molecular cell research2017

Pathological consequences of MICU1 mutations on mitochondrial calcium signalling and bioenergetics.

Gauri Bhosale, Jenny A Sharpe, Amanda Koh, Antonina Kouli, Gyorgy Szabadkai, Michael R Duchen

Open access · hybridAbstract read
In one paragraph

Article in Biochimica et biophysica acta. Molecular cell research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 57 citations in OpenAlex.

  1. Article
  2. The two faces of mitochondrial CaJournal of physiology and biochemistry · 2026
    Review
  3. Review
  4. MICU1's calcium sensing beyond mitochondrial calcium uptake.Biochimica et biophysica acta. Molecular cell research · 2024
    Review
  5. Article
  6. Review
  7. Review
  8. MICU1 occludes the mitochondrial calcium uniporter in divalent-free conditions.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Article
  14. Pharmacological inhibition of the mitochondrial CaJournal of molecular and cellular cardiology · 2021
    Review
  15. Article
  16. Mitochondrial CaActa pharmacologica Sinica · 2020
    Review
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Gauri BhosaleDepartment of Cell and Developmental Biology, University College London, Gower Street, London WC1E 6BT, United Kingdom.
Jenny A SharpeDepartment of Cell and Developmental Biology, University College London, Gower Street, London WC1E 6BT, United Kingdom.
Amanda KohDepartment of Cell and Developmental Biology, University College London, Gower Street, London WC1E 6BT, United Kingdom.
Antonina KouliDepartment of Cell and Developmental Biology, University College London, Gower Street, London WC1E 6BT, United Kingdom.
Gyorgy SzabadkaiDepartment of Cell and Developmental Biology, University College London, Gower Street, London WC1E 6BT, United Kingdom; Department of Biomedical Sciences, University of Padua, 35131 Padua, Italy.
Michael R DuchenDepartment of Cell and Developmental Biology, University College London, Gower Street, London WC1E 6BT, United Kingdom. Electronic address: m.duchen@ucl.ac.uk.
University College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Loss of function mutations of the protein MICU1, a regulator of mitochondrial Ca

Indexed as

Calcium SignalingEnergy MetabolismMutationCalcium-Binding ProteinsCation Transport ProteinsCells, CulturedHumansMitochondriaMitochondrial Membrane Transport ProteinsCalcium-Binding ProteinsCation Transport ProteinsMICU1 protein, humanMitochondrial Membrane Transport ProteinsCalciumMICU1MitochondriaPDH

Identifiers

PMID28132899
PMCPMC5424885
OpenAlexW2583026377

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.