Evidence map›Paper›PMID 28132857›Full record

ArticleThe Journal of investigative dermatology2017

IL-27 Facilitates Skin Wound Healing through Induction of Epidermal Proliferation and Host Defense.

Bin Yang, Jutamas Suwanpradid, Roberto Sanchez-Lagunes, Hae Woong Choi, Peter Hoang, Donghai Wang, Soman N Abraham, Amanda S MacLeod

Open access · hybridAbstract read
In one paragraph

Article in The Journal of investigative dermatology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
5.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 57 citations in OpenAlex.

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  9. A review with updated perspectives on in vitro and in vivo wound healing models.Turkish journal of biology = Turk biyoloji dergisi · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 2 countries.

Bin YangDepartment of Dermatology, Duke University School of Medicine, Durham, North Carolina, USA; Department of Dermatology, Wuhan General Hospital of Guangzhou Command, Wuhan, China.
Jutamas SuwanpradidDepartment of Dermatology, Duke University School of Medicine, Durham, North Carolina, USA.
Roberto Sanchez-LagunesDepartment of Dermatology, Duke University School of Medicine, Durham, North Carolina, USA.
Hae Woong ChoiDepartment of Pathology, Duke University School of Medicine, Durham, North Carolina, USA.
Peter HoangDepartment of Dermatology, Duke University School of Medicine, Durham, North Carolina, USA.
Donghai WangDepartment of Medicine, Duke University School of Medicine, Durham, North Carolina, USA; Department of Immunology, Duke University School of Medicine, Durham, North Carolina, USA.
Soman N AbrahamDepartment of Pathology, Duke University School of Medicine, Durham, North Carolina, USA; Department of Immunology, Duke University School of Medicine, Durham, North Carolina, USA.
Amanda S MacLeodDepartment of Dermatology, Duke University School of Medicine, Durham, North Carolina, USA; Department of Immunology, Duke University School of Medicine, Durham, North Carolina, USA. Electronic address: Amanda.MacLeod@duke.edu.
Duke University · US

Funding

ATP in Skin ImmunityK08AR063729 · NIAMS · SCRIPPS RESEARCH INSTITUTE, THE · PI MACLEOD, AMANDA S · 2013 to 2017
$636k
NIAMS NIH HHS K08 AR063729
6 · The paper itself

Abstract

Skin wound repair requires a coordinated program of epithelial cell proliferation and differentiation as well as resistance to invading microbes. However, the factors that trigger epithelial cell proliferation in this inflammatory process are incompletely understood. In this study, we demonstrate that IL-27 is rapidly and transiently produced by CD301b

Indexed as

AnimalsCell DifferentiationCell ProliferationCells, CulturedDisease Models, AnimalEpithelial CellsHumansInterleukin-27KeratinocytesLectins, C-TypeMiceMice, KnockoutReceptors, CytokineReceptors, InterleukinSignal TransductionSkinIl27ra protein, mouseInterleukin-27Lectins, C-TypeMGL2 protein, mouseReceptors, CytokineReceptors, Interleukin

Identifiers

PMID28132857
PMCPMC5552041
OpenAlexW2343141742

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.