Evidence map›Paper›PMID 28132744›Full record

ArticleThe Journal of adolescent health : official publication of the Society for Adolescent Medicine2017

Young Transgender Women's Attitudes Toward HIV Pre-exposure Prophylaxis.

Sarah M Wood, Susan Lee, Frances K Barg, Marne Castillo, Nadia Dowshen

Abstract read
In one paragraph

Article in The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sarah M WoodCraig Dalsimer Division of Adolescent Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania; Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania. Electronic address: woodsa@email.chop.edu.
Susan LeeCraig Dalsimer Division of Adolescent Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Frances K BargDepartment of Family Health and Community Health, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.
Marne CastilloCraig Dalsimer Division of Adolescent Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Nadia DowshenCraig Dalsimer Division of Adolescent Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania; Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.

Funding

Virus & Reservoirs CoreP30AI045008 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI DAVID S METZGER · 1999 to 2026
$78.6M
Penn Mental Health AIDS Research CenterP30MH097488 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI Karine Dube · 2013 to 2026
$23.5M
mHealth intervention for ART adherence and sexual risk reduction among HIV+ YMSMK23MH102128 · NIMH · CHILDREN'S HOSP OF PHILADELPHIA · PI DOWSHEN, NADIA L · 2014 to 2018
$875k
Social Support as a Facilitator of Adherence to HIV Pre-Exposure Prophylaxis Among Young MSM of ColorF32MH111341 · NIMH · CHILDREN'S HOSP OF PHILADELPHIA · PI WOOD, SARAH MARIAN · 2016 to 2018
$145k
NIAID NIH HHS P30 AI045008NIMH NIH HHS F32 MH111341NIMH NIH HHS K23 MH102128NIMH NIH HHS P30 MH097488
6 · The paper itself

Abstract

purposeOur primary aim was to explore themes regarding attitudes toward HIV pre-exposure prophylaxis (PrEP) among young transgender women (YTW), in order to develop a theoretical model of PrEP uptake in this population disproportionally affected by HIV.

methodsQualitative study nested within a mixed-method study characterizing barriers and facilitators to health services for YTW. Participants completed an in-depth interview exploring awareness of and attitudes toward PrEP. Key themes were identified using a grounded theory approach.

resultsParticipants (n = 25) had a mean age of 21.2 years (standard deviation 2.2, range 17-24) and were predominately multiracial (36%) and of HIV-negative or unknown status (68%). Most participants (64%) reported prior knowledge of PrEP, and 28% reported current use or intent to use PrEP. Three major content themes that emerged were variability of PrEP awareness, barriers and facilitators to PrEP uptake, and emotional benefits of PrEP. Among participants without prior PrEP knowledge, participants reported frustration that PrEP information has not been widely disseminated to YTW, particularly by health care providers. Attitudes toward PrEP were overwhelmingly positive; however, concerns were raised regarding barriers including cost, stigma, and adherence challenges. Both HIV-positive and negative participants discussed emotional and relationship benefits of PrEP, which were felt to extend beyond HIV prevention alone.

conclusionsA high proportion of YTW in this study had prior knowledge of PrEP, and attitudes toward PrEP were positive among participants. Our findings suggest several domains to be further explored in PrEP implementation research, including methods of facilitating PrEP dissemination and emotional motivation for PrEP uptake.

Indexed as

Health Knowledge, Attitudes, PracticeHealth Services AccessibilityPre-Exposure ProphylaxisAdolescentCross-Sectional StudiesFemaleGrounded TheoryHIV InfectionsHumansMaleQualitative ResearchSelf EfficacyTransgender PersonsYoung AdultHIV pre-exposure prophylaxisHIV preventionQualitative researchTransgender women

Identifiers

PMID28132744
PMCPMC5401785

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.