Evidence map›Paper›PMID 28132187›Full record

ArticleNeuroinformatics2017

Combining a Patch-based Approach with a Non-rigid Registration-based Label Fusion Method for the Hippocampal Segmentation in Alzheimer's Disease.

Carlos Platero, M Carmen Tobar

Abstract read
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In one paragraph

Article in Neuroinformatics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Carlos PlateroHealth Science Technology Group, Technical University of Madrid, Ronda de Valencia 3, 28012, Madrid, Spain. carlos.platero@upm.es.
M Carmen TobarHealth Science Technology Group, Technical University of Madrid, Ronda de Valencia 3, 28012, Madrid, Spain.
Universidad Politécnica de Madrid · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We provide and evaluate an open-source software solution for automatically hippocampal segmentation from T1-weighted (T1w) magnetic resonance imaging (MRI). The method is applied for measuring the hippocampal volume, which allows discriminate between patients with Alzheimer's disease (AD) or mild cognitive impairment (MCI) and elderly controls (NC). The method is based on a fast patch-based label fusion method, whose selected patches and their weights are calculated from a combination of similarity measures between patches using intensity-based distances and labeling-based distances. These combined similarity measures produces better selection of the patches, and their weights are more robust. The algorithm is trained with the Harmonized Hippocampal Protocol (HarP). The proposal is compared with FreeSurfer and other label fusion methods. To evaluate the performance and the robustness of the proposed label fusion method, we employ two databases of T1w MRI of human brains. For AD vs NC, we obtain a high degree of accuracy, approximately 90 %. For MCI vs NC, we obtain accuracies around 75 %. The average time for the hippocampal segmentation from a T1w MRI is less than 17 minutes.

Indexed as

Image Processing, Computer-AssistedMagnetic Resonance ImagingAgedAged, 80 and overAlzheimer DiseaseAnalysis of VarianceCognitive DysfunctionDatabases, FactualFemaleHippocampusHumansMaleMental Status SchedulePattern Recognition, AutomatedAtlas-based segmentationHippocampal segmentationImage registrationMagnetic resonance imagingPatch-based label fusion

Identifiers

PMID28132187
OpenAlexW2583043129

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.