Evidence map›Paper›PMID 28132130›Full record

ArticleCellular and molecular neurobiology2017

Rab10 Disruption Results in Delayed OPC Maturation.

Zhao-Huan Zhang, Wei-Qian Zhao, Fan-Fei Ma, Hui Zhang, Xiao-Hui Xu

Open access · greenAbstract read
In one paragraph

Article in Cellular and molecular neurobiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Zhao-Huan ZhangSchool of Life Sciences, Shanghai University, Shanghai, 200444, China.
Wei-Qian ZhaoSchool of Life Sciences, Shanghai University, Shanghai, 200444, China.
Fan-Fei MaSchool of Life Sciences, Shanghai University, Shanghai, 200444, China.
Hui ZhangSchool of Life Sciences, Shanghai University, Shanghai, 200444, China.
Xiao-Hui XuSchool of Life Sciences, Shanghai University, Shanghai, 200444, China. xxhxxh@shu.edu.cn.
Shanghai University · CN

Funding

National Natural Science Foundation of China 31470053National Natural Science Foundation of China 81370031National Natural Science Foundation of China 81671263
6 · The paper itself

Abstract

Oligodendrocyte precursor cell (OPC) maturation requires membrane addition for myelin sheath formation. Since the Rab system has been shown to contribute to membrane addition in other cell types, in this study, we explored the role of Rab in OPC maturation. SiRNA and shRNA techniques and conditional knockout mice provided in vitro and in vivo evidence that Rab10 is involved in OPC maturation and may affect myelination during OPC development.

Indexed as

AnimalsAnimals, NewbornCells, CulturedMiceMice, KnockoutMice, TransgenicOligodendrocyte Precursor CellsOligodendrogliarab GTP-Binding ProteinsRatsRats, Sprague-DawleyRab10 protein, mouserab GTP-Binding ProteinsMaturationMBPMembrane additionOPCRab10

Identifiers

PMID28132130
PMCPMC11482111
OpenAlexW2580208280

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.