ArticleEuropean journal of nuclear medicine and molecular imaging2017
The added value of SPECT-CT for the identification of sentinel lymph nodes in early stage oral cancer.
Article in European journal of nuclear medicine and molecular imaging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 34 citations in OpenAlex.
- Nuclear medicine in the operating room: present and future.The British journal of radiology · 2026Review
- Sentinel Lymph Node Detection in Early-Stage Oral Squamous Cell Carcinoma Using Magnetic Resonance Lymphography: A Pilot Study.Journal of clinical medicine · 2024Article
- CT Lymphography Using LipiodolJournal of clinical medicine · 2022Article
- Evaluation of a streamlined sentinel lymph-node imaging protocol in early-stage oral cancer.Annals of nuclear medicine · 2021Article
- What is the role of sentinel lymph node biopsy in the management of oral cancer in 2020?European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2021Review
- MR lymphography with superparamagnetic iron oxide for sentinel lymph node mapping of N0 early oral cancer: A pilot study.Dento maxillo facial radiology · 2021Article
- Sentinel lymph node mapping of clinically N0 early oral cancer: a diagnostic pitfall on CT lymphography.Oral radiology · 2021Article
- Can Sentinel Lymph Node Biopsy Predict Various Levels of Echelon Nodes in Oral Cancers?International archives of otorhinolaryngology · 2020Article
- CT lymphography for sentinel lymph node mapping of clinically N0 early oral cancer.Cancer imaging : the official publication of the International Cancer Imaging Society · 2019Article
- Two decades of SPECT/CT - the coming of age of a technology: An updated review of literature evidence.European journal of nuclear medicine and molecular imaging · 2019Review
- Depth of invasion in patients with early stage oral cancer staged by sentinel node biopsy.Head & neck · 2019Article
- SPECT/CT-guided lymph drainage mapping for the planning of unilateral elective nodal irradiation in head and neck squamous cell carcinoma.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2018Article
- Feasibility of intraoperative detection of sentinel lymph nodes with 89-zirconium-labelled nanocolloidal albumin PET-CT and a handheld high-energy gamma probe.EJNMMI research · 2018Article
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7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo assess the role of single-photon emission computed tomography with computed tomography (SPECT-CT) for the identification of sentinel lymph nodes (SLNs) in patients with early stage (T1-T2) oral cancer and a clinically negative neck (cN0).
methodsIn addition to planar lymphoscintigraphy, SPECT-CT was performed in 66 consecutive patients with early stage oral cancer and a clinically negative neck. The addition of SPECT-CT to planar images was retrospectively analyzed for the number of additional SLNs, more precise localization of SLNs, and importance of anatomical information by a team consisting of a nuclear physician, surgeon, and investigator.
resultsIdentification rate for both imaging modalities combined was 98% (65/66). SPECT-CT identified 15 additional SLNs in 14 patients (22%). In 2/15 (13%) of these additional SLNs, the only metastasis was found, resulting in an upstaging rate of 3% (2/65). In 20% of the patients with at least one positive SLN, the only positive SLN was detected due to the addition of SPECT-CT. SPECT-CT was considered to add important anatomical information in two patients (3%). In 5/65 (8%) of the patients initially scored SLNs on planar lymphoscintigrams were scored as non-SLNs when SPECT-CT was added. There were four false-negative SLN biopsy procedures in this cohort.
conclusionsThe addition of SPECT-CT to planar lymphoscintigraphy is recommended for the identification of more (positive) SLNs and better topographical orientation for surgery in sentinel lymph node biopsy for early stage oral cancer.
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