Evidence map›Paper›PMID 28132098›Full record

ReviewDysphagia2017

Animal Models for Dysphagia Studies: What Have We Learnt So Far.

Rebecca Z German, A W Crompton, Francois D H Gould, Allan J Thexton

Abstract readReview
In one paragraph

Review in Dysphagia, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Research advances in dysphagia animal models.Animal models and experimental medicine · 2025
    Review
  9. Article
  10. Longitudinal Changes in Aerodigestive Responses to Varying Nipple Properties in Infant Pigs.Journal of experimental zoology. Part A, Ecological and integrative physiology · 2025
    Article
  11. Article
  12. The effects of simulated gastroesophageal reflux on infant pig oropharyngeal feeding physiology.American journal of physiology. Gastrointestinal and liver physiology · 2024
    Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Nipple properties affect sensorimotor integration during bottle feeding in an infant pig model.Journal of experimental zoology. Part A, Ecological and integrative physiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rebecca Z GermanDepartment of Anatomy and Neuroscience, Northeast Ohio Medical University, Rootstown, OH, 444272, USA. rgerman@neomed.edu.ORCID 0000-0001-9989-7847
A W CromptonMuseum of Comparative Zoology, Harvard University, Cambridge, MA, 02138, USA.
Francois D H GouldDepartment of Anatomy and Neuroscience, Northeast Ohio Medical University, Rootstown, OH, 444272, USA.
Allan J ThextonDivision of Physiology, King's College, Guy's Campus, London, SE1 9RT, UK.

Funding

The Effect of Preterm Birth and RLN Damage on Airway Protection and MaturationR01HD088561 · NICHD · NORTHEAST OHIO MEDICAL UNIVERSITY · PI GERMAN, REBECCA Z · 2016 to 2020
$2.4M
Dysphagia and Recovery After Vagal or Laryngeal Nerve InjuryR01DC009980 · NIDCD · NORTHEAST OHIO MEDICAL UNIVERSITY · PI GERMAN, REBECCA Z · 2010 to 2014
$2.0M
DIFFERENCES IN SWALLOW MECHANICS IN INFANTSR01DC003604 · NIDCD · UNIVERSITY OF CINCINNATI · PI GERMAN, REBECCA Z · 1998 to 2005
$1.8M
Dysphagia in Induced Parkinson's DiseaseR21DC006953 · NIDCD · UNIVERSITY OF CINCINNATI · PI GERMAN, REBECCA Z · 2004 to 2005
$380k
Semiparametric inference of survival dataZ01HD008856 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI SUNDARAM, RAJESHWARI · 2008 to 2008
$109k
PARATHYROID HORMONE RELATED PROTEIN AND TOOTH ERUPTIONF32DE005738 · NIDCR · YALE UNIVERSITY · PI NAKCHBANDI, INAAM A · 1999 to 1999
–
Intramural NIH HHS Z01 HD008856NICHD NIH HHS R01 HD088561NIDCD NIH HHS R01 DC003604NIDCD NIH HHS R01 DC009980NIDCD NIH HHS R21 DC006953NIDCR NIH HHS F32 DE005738
6 · The paper itself

Abstract

Research using animal models has contributed significantly to realizing the goal of understanding dysfunction and improving the care of patients who suffer from dysphagia. But why should other researchers and the clinicians who see patients day in and day out care about this work? Results from studies of animal models have the potential to change and grow how we think about dysphagia research and practice in general, well beyond applying specific results to human studies. Animal research provides two key contributions to our understanding of dysphagia. The first is a more complete characterization of the physiology of both normal and pathological swallow than is possible in human subjects. The second is suggesting of specific, physiological, targets for development and testing of treatment interventions to improve dysphagia outcomes.

Indexed as

Disease Models, AnimalAnimalsBiomedical ResearchDeglutitionDeglutition DisordersHumansAnimal modelsDeglutitionDeglutition disordersPathophysiologyPerformance

Identifiers

PMID28132098
PMCPMC5545751

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.