Evidence map›Paper›PMID 28131772›Full record

ArticleArchives of biochemistry and biophysics2017

In vitro actin motility velocity varies linearly with the number of myosin impellers.

Y Wang, T P Burghardt

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Archives of biochemistry and biophysics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Y WangDepartment of Biochemistry and Molecular Biology, Mayo Clinic Rochester, Rochester, MN 55905, United States.
T P BurghardtDepartment of Biochemistry and Molecular Biology, Mayo Clinic Rochester, Rochester, MN 55905, United States; Department of Physiology and Biomedical Engineering, Mayo Clinic Rochester, Rochester, MN 55905, United States. Electronic address: burghardt@mayo.edu.
Mayo Clinic · US

Funding

Visualizing Actomyosin Transients by Data MergingR01AR049277 · NIAMS · MAYO CLINIC ROCHESTER · PI BURGHARDT, THOMAS P · 2004 to 2013
$3.2M
NIAMS NIH HHS R01 AR049277
6 · The paper itself

Abstract

Cardiac myosin is the motor powering the heart. It moves actin with 3 step-size varieties generated by torque from the myosin heavy chain lever-arm rotation under the influence of myosin essential light chain whose N-terminal extension binds actin. Proposed mechanisms adapting myosin mechanochemical characteristics on the fly sometimes involve modulation of step-size selection probability via motor strain sensitivity. Strain following the power stroke, hypothetically imposed by the finite actin detachment rate 1/t

Indexed as

Actin CytoskeletonActinsAdenosine TriphosphatasesAdenosine TriphosphateAdsorptionAnimalsCardiac MyosinsCell MovementCross-Linking ReagentsHeart VentriclesHydrogen-Ion ConcentrationKineticsProbabilityProtein DomainsSolubilitySwineActinsAdenosine TriphosphatasesAdenosine TriphosphateCardiac MyosinsCross-Linking ReagentsActin detachment limited velocityEnsemble myosin strain sensingIndependent force generatorRandom walk step-sizeVelocity histogram probability characteristic

Identifiers

PMID28131772
PMCPMC5472206
OpenAlexW2580703137

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.