Evidence map›Paper›PMID 28131015›Full record

ArticleNeurobiology of aging2017

Amyloid and intracellular accumulation of BRI

Holly J Garringer, Neeraja Sammeta, Adrian Oblak, Bernardino Ghetti, Ruben Vidal

Open access · greenAbstract read
In one paragraph

Article in Neurobiology of aging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Holly J GarringerDepartment of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, USA; Indiana Alzheimer Disease Center, Indiana University School of Medicine, Indianapolis, IN, USA.
Neeraja SammetaDepartment of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.
Adrian OblakDepartment of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, USA; Indiana Alzheimer Disease Center, Indiana University School of Medicine, Indianapolis, IN, USA.
Bernardino GhettiDepartment of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, USA; Indiana Alzheimer Disease Center, Indiana University School of Medicine, Indianapolis, IN, USA.
Ruben VidalDepartment of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, USA; Indiana Alzheimer Disease Center, Indiana University School of Medicine, Indianapolis, IN, USA. Electronic address: rvidal@iupui.edu.
Indiana University – Purdue University Indianapolis · USIndiana University School of Medicine

Funding

Research Education ComponentP30AG010133 · NIA · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI SAYKIN, ANDREW J · 1991 to 2020
$37.3M
Ferritin Induced NeurodegenerationR01NS050227 · NINDS · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI VIDAL, RUBEN · 2005 to 2015
$3.1M
Non-amyloidogenic processing of APPR21AG037338 · NIA · INDIANA UNIVERSITY INDIANAPOLIS · PI VIDAL, RUBEN · 2011 to 2012
$347k
NIA NIH HHS P30 AG010133NIA NIH HHS R21 AG037338NINDS NIH HHS R01 NS050227
6 · The paper itself

Abstract

Familial British dementia (FBD) and familial Danish dementia (FDD) are caused by mutations in the BRI

Indexed as

Genetic Association StudiesAdaptor Proteins, Signal TransducingAlzheimer DiseaseAmyloid Neuropathies, FamilialAmyloidogenic ProteinsAnimalsBrainCataractCells, CulturedCerebellar AtaxiaCerebral Amyloid Angiopathy, FamilialDeafnessDementiaGerstmann-Straussler-Scheinker DiseaseGolgi ApparatusMembrane GlycoproteinsAdaptor Proteins, Signal TransducingAmyloidogenic ProteinsITM2B protein, humanMembrane GlycoproteinsAlzheimer diseaseAmyloidBRI(2)Familial British dementiaFamilial Danish dementiaGerstmann-Sträussler-Scheinker disease

Identifiers

PMID28131015
PMCPMC5359036
OpenAlexW2566918515

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.