Evidence map›Paper›PMID 28130845›Full record

ArticleGlia2017

Neuron-astrocyte signaling is preserved in the aging brain.

Marta Gómez-Gonzalo, Mario Martin-Fernandez, Ricardo Martínez-Murillo, Sara Mederos, Alicia Hernández-Vivanco, Stephanie Jamison, Ana P Fernandez, Julia Serrano, Pilar Calero, Hunter S Futch and 4 more

Open access · greenAbstract read
In one paragraph

Article in Glia, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 114 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Astrocytes in aging.Neuron · 2025
    Review
  8. Article
  9. Activation of Bradykinin BInternational journal of molecular sciences · 2024
    Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Optogenetics in Alzheimer's Disease: Focus on Astrocytes.Antioxidants (Basel, Switzerland) · 2023
    Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Dysregulation of astrocytic CaActa neuropathologica · 2023
    Article

15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 2 countries.

Marta Gómez-GonzaloInstituto Cajal, CSIC, Madrid, 28002, Spain.
Mario Martin-FernandezDepartment of Neuroscience, University of Minnesota, Minneapolis, 55455.
Ricardo Martínez-MurilloInstituto Cajal, CSIC, Madrid, 28002, Spain.
Sara MederosInstituto Cajal, CSIC, Madrid, 28002, Spain.
Alicia Hernández-VivancoInstituto Cajal, CSIC, Madrid, 28002, Spain.
Stephanie JamisonDepartment of Neuroscience, University of Minnesota, Minneapolis, 55455.
Ana P FernandezInstituto Cajal, CSIC, Madrid, 28002, Spain.
Julia SerranoInstituto Cajal, CSIC, Madrid, 28002, Spain.
Pilar CaleroInstituto Cajal, CSIC, Madrid, 28002, Spain.
Hunter S FutchCollege of Medicine, University of Florida, Gainesville, Florida, 32610-0261.
Rubén CorpasAging and Neurodegeneration Unit, Biomedical Research Institute of Barcelona (IIBB), CSIC and IDIBAPS, Barcelona, 08036, Spain.
Coral SanfeliuAging and Neurodegeneration Unit, Biomedical Research Institute of Barcelona (IIBB), CSIC and IDIBAPS, Barcelona, 08036, Spain.
Gertrudis PereaInstituto Cajal, CSIC, Madrid, 28002, Spain.
Alfonso AraqueDepartment of Neuroscience, University of Minnesota, Minneapolis, 55455.
Instituto Cajal · ESUniversity of Minnesota · USConsorci Institut D'Investigacions Biomediques August Pi I Sunyer · ESFlorida College · USInstitut d'Investigacions Biomèdiques de Barcelona · ES

Funding

Astrocyte-neuron interaction in behavior driven by striatal information processingR01NS097312 · NINDS · UNIVERSITY OF MINNESOTA · PI ARAQUE, ALFONSO, REDISH, A DAVID · 2016 to 2019
$1.8M
NINDS NIH HHS R01 NS097312
6 · The paper itself

Abstract

Astrocytes play crucial roles in brain homeostasis and are emerging as regulatory elements of neuronal and synaptic physiology by responding to neurotransmitters with Ca

Indexed as

AgingAcetylcholineAdenosine TriphosphateAmyloid beta-Protein PrecursorAnimalsAstrocytesBrainCalciumCell CommunicationExcitatory Amino Acid AgentsMembrane PotentialsMethoxyhydroxyphenylglycolMiceMice, Inbred C57BLMice, TransgenicNeurons3,4-dihydroxyphenylglycolAcetylcholineAdenosine TriphosphateAmyloid beta-Protein PrecursorCalciumExcitatory Amino Acid AgentsMethoxyhydroxyphenylglycolPresenilin-1presenilin 1, mouseastrocytesbrain aginggliotransmissionneuron-glia signalingsynaptic plasticity

Identifiers

PMID28130845
PMCPMC5314210
OpenAlexW2580929144

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.