ArticleThe journal of headache and pain2017
Simulated airplane headache: a proxy towards identification of underlying mechanisms.
Article in The journal of headache and pain, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Headache attributed to airplane travel: diagnosis, pathophysiology, and treatment - a systematic review.The journal of headache and pain · 2017Pooled it
- Rimegepant in airplane headache treatment: a case report.Journal of medical case reports · 2025Article
- The epidemiology of airplane headache: A cross-sectional study on point prevalence and characteristics in 50,000 travelers.Cephalalgia : an international journal of headache · 2022Article
- Sherpas, Coca Leaves, and Planes: High Altitude and Airplane Headache Review with a Case of Post-LASIK Myopic Shift.Current neurology and neuroscience reports · 2019Review
- Headache and Barometric Pressure: a Narrative Review.Current pain and headache reports · 2019Review
- Diving Headache.Current pain and headache reports · 2019Review
- Headache attributed to aeroplane travel: the first multicentric survey in a paediatric population affected by primary headaches.The journal of headache and pain · 2018Article
- Headache Attributed to Airplane Travel: A Review of Literature.Current pain and headache reports · 2018Review
- Successful Treatment of Airplane Headache with Rizatriptan: Case Report.Case reports in neurologyArticle
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAirplane Headache (AH) occurs during flights and often appears as an intense, short lasting headache during take-off or landing. Reports are limited on pathological mechanisms underlying the occurrence of this headache. Proper diagnosis and treatments would benefit from identification of potential pathways involved in AH pathogenesis. This study aimed at providing a simulated airplane headache condition as a proxy towards identification of its underlying mechanisms.
methodsFourteen participants including 7 volunteers suffering from AH and 7 healthy matched controls were recruited after meeting the diagnostic and safety criteria based on an approved study protocol. Simulation of AH was achieved by entering a pressure chamber with similar characteristics of an airplane flight. Selected potential biomarkers including salivary prostaglandin E
resultsAll participants in the AH-group experienced a headache attack similar to AH experience during flight. The non-AH-group did not experience any headaches. Our data showed that the values for PGE
conclusionThe pressure chamber proved useful not only to provoke AH-like attack but also to study potential biomarkers for AH in this study. PGE
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.