ReviewGastroenterology report2017
Current status of intestinal and multivisceral transplantation.
Review in Gastroenterology report, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 68 citations in OpenAlex.
- Home Parenteral Support in Severe Gitelman Syndrome: A Case Report.Clinical case reports · 2026Article
- A standardised and reproducible method forAnnals of translational medicine · 2026Article
- Classic multivisceral transplant for advanced nonresectable pseudomyxoma peritonei: a case report.Journal of medical case reports · 2025Article
- MHC Class II Sharing Appears to Promote Intestinal Allograft Tolerance Through Linked Suppression in a Large Animal Model.Transplantation · 2025Article
- Impact of Recipient and Donor Body Mass Index on Survival Outcomes After Intestinal Transplantation: A United Network for Organ Sharing Database Analysis.Annals of transplantation · 2024Article
- Normothermic Preservation of the Intestinal Allograft.Gastroenterology clinics of North America · 2024Review
- Comparison of the effects of normothermic machine perfusion and cold storage preservation on porcine intestinal allograft regenerative potential and viability.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2024Article
- Intestinal Donation and Utilization: Single-Center Analysis Within Eurotransplant.Transplant international : official journal of the European Society for Organ Transplantation · 2023Article
- Overview of Physical, Neurocognitive, and Psychosocial Outcomes in Pediatric Intestinal Failure and Transplantation.Current gastroenterology reports · 2022Review
- [Chronic intestinal failure].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2022Article
- Optical coherence tomography of small intestine allograft biopsies using a handheld surgical probe.Journal of biomedical optics · 2021Article
- Short-Bowel Syndrome: Epidemiology, Hospitalization Trends, In-Hospital Mortality, and Healthcare Utilization.JPEN. Journal of parenteral and enteral nutrition · 2021Article
- Neurodevelopmental and Growth Outcomes of Extremely Preterm Infants with Short Bowel Syndrome.The Journal of pediatrics · 2021Article
- Surgical Resection of Native Viscera to Manage Persistent Ascites after Multivisceral Transplant.Case reports in transplantation · 2020Article
- R-Spondin 1 (RSPO1) Increases Mouse Intestinal Organoid Unit Size and SurvivalFrontiers in bioengineering and biotechnology · 2020Article
- Variable management strategies for NEC totalis: a national survey.Journal of perinatology : official journal of the California Perinatal Association · 2019Article
- Familial Adenomatous Polyposis and Desmoid Tumor Treated with Multivisceral Transplantation and Kidney Autotransplantation: Case Report and Literature Review.Case reports in surgery · 2019Article
- Liver-inclusive intestinal transplantation results in decreased alloimmune-mediated rejection but increased infection.Gastroenterology report · 2018Article
- Identifying the Growth Factors for Improving Neointestinal Regeneration in Rats through Transcriptome Analysis Using RNA-Seq Data.BioMed research international · 2018Article
- Diagnostic Lessons from a Complex Case of Postintestinal Transplantation Enteropathy.Case reports in transplantation · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Clinical-nutritional autonomy is the ultimate goal of patients with intestinal failure (IF). Traditionally, patients with IF have been relegated to lifelong parenteral nutrition (PN) once surgical and medical rehabilitation attempts at intestinal adaptation have failed. Over the past two decades, however, outcome improvements in intestinal transplantation have added another dimension to the therapeutic armamentarium in the field of gut rehabilitation. This has become possible through relentless efforts in the standardization of surgical techniques, advancements in immunosuppressive therapies and induction protocols and improvement in postoperative patient care. Four types of intestinal transplants include isolated small bowel transplant, liver-small bowel transplant, multivisceral transplant and modified multivisceral transplant. Current guidelines restrict intestinal transplantation to patients who have had significant complications from PN including liver failure and repeated infections. From an experimental stage to the currently established therapeutic modality for patients with advanced IF, outcome improvements have also been possible due to the introduction of tacrolimus in the early 1990s. Studies have shown that intestinal transplant is cost-effective within 1-3 years of graft survival compared with PN. Improved survival and quality of life as well as resumption of an oral diet should enable intestinal transplantation to be an important option for patients with IF in addition to continued rehabilitation. Future research should focus on detecting biomarkers of early rejection, enhanced immunosuppression protocols, improved postoperative care and early referral to transplant centers.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.