Evidence map›Paper›PMID 28130342›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2017

NFAT regulation of cystathionine γ-lyase expression in endothelial cells is impaired in rats exposed to intermittent hypoxia.

Laura V Gonzalez Bosc, Jessica M Osmond, Wieslawa K Giermakowska, Carolyn E Pace, Jennifer L Riggs, Olan Jackson-Weaver, Nancy L Kanagy

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Endothelium as a Source and Target of HAntioxidants (Basel, Switzerland) · 2021
    Review
  5. Simulated sleep apnea alters hydrogen sulfide regulation of blood flow and pressure.American journal of physiology. Heart and circulatory physiology · 2021
    Article
  6. Article
  7. Article
  8. Hydrogen sulfide regulation of renal and mesenteric blood flow.American journal of physiology. Heart and circulatory physiology · 2019
    Article
  9. Statistical considerations in reporting cardiovascular research.American journal of physiology. Heart and circulatory physiology · 2018
    Article
  10. Mechanisms of I/R-Induced Endothelium-Dependent Vasodilator Dysfunction.Advances in pharmacology (San Diego, Calif.) · 2018
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Laura V Gonzalez BoscVascular Physiology Group, Department of Cell Biology and Physiology, University of New Mexico Health Sciences Center, Albuquerque, New Mexico.
Jessica M OsmondVascular Physiology Group, Department of Cell Biology and Physiology, University of New Mexico Health Sciences Center, Albuquerque, New Mexico.
Wieslawa K GiermakowskaVascular Physiology Group, Department of Cell Biology and Physiology, University of New Mexico Health Sciences Center, Albuquerque, New Mexico.
Carolyn E PaceVascular Physiology Group, Department of Cell Biology and Physiology, University of New Mexico Health Sciences Center, Albuquerque, New Mexico.
Jennifer L RiggsVascular Physiology Group, Department of Cell Biology and Physiology, University of New Mexico Health Sciences Center, Albuquerque, New Mexico.
Olan Jackson-WeaverVascular Physiology Group, Department of Cell Biology and Physiology, University of New Mexico Health Sciences Center, Albuquerque, New Mexico.
Nancy L KanagyVascular Physiology Group, Department of Cell Biology and Physiology, University of New Mexico Health Sciences Center, Albuquerque, New Mexico nkanagy@salud.unm.edu.
University of New Mexico · US

Funding

MINORITY INSTITUTIONAL RESEARCH TRAINING PROGRAM (T32)T32HL007736 · NHLBI · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI RESTA, THOMAS C · 1993 to 2025
$6.5M
Hydrogen sulfide regulation of vascular tone and blood pressureR01HL123301 · NHLBI · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI KANAGY, NANCY L · 2015 to 2018
$1.5M
NHLBI NIH HHS R01 HL123301NHLBI NIH HHS T32 HL007736
6 · The paper itself

Abstract

Sleep apnea is a risk factor for cardiovascular disease, and intermittent hypoxia (IH, 20 episodes/h of 5% O

Indexed as

AcetylcholineAnimalsBase SequenceCalcineurinCalciumCells, CulturedCystathionine gamma-LyaseEndothelial CellsHydrogen SulfideHypoxiaMaleMesenteric ArteriesNFATC Transcription FactorsRatsRats, Sprague-DawleySleep Apnea SyndromesAcetylcholineCalcineurinCalciumCystathionine gamma-LyaseHydrogen SulfideNFATC Transcription FactorsVasodilator Agentscalcineurinhydrogen sulfidemesenteric arteriesnuclear factor of activated T cells c3sleep apneavasodilation

Identifiers

PMID28130342
PMCPMC5407154
OpenAlexW2580350471

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.