Evidence map›Paper›PMID 28130041›Full record

ArticleAmerican journal of ophthalmology2017

Detecting Change Using Standard Global Perimetric Indices in Glaucoma.

Stuart K Gardiner, Shaban Demirel

Open access · greenAbstract readComparative Study
In one paragraph

Article in American journal of ophthalmology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 35 citations in OpenAlex.

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  16. Detection of Functional Change Using Cluster Trend Analysis in Glaucoma.Investigative ophthalmology & visual science · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Stuart K GardinerDevers Eye Institute, Legacy Research Institute, Portland, Oregon. Electronic address: sgardiner@deverseye.org.
Shaban DemirelDevers Eye Institute, Legacy Research Institute, Portland, Oregon.
Legacy Health · US

Funding

Functional Testing for GlaucomaR01EY020922 · NEI · LEGACY EMANUEL HOSPITAL AND HEALTH CENTER · PI GARDINER, STUART · 2011 to 2021
$3.2M
Predicting the rate of progression in glaucomaR01EY019674 · NEI · LEGACY EMANUEL HOSPITAL AND HEALTH CENTER · PI DEMIREL, SHABAN · 2009 to 2013
$1.8M
NEI NIH HHS R01 EY019674NEI NIH HHS R01 EY020922
6 · The paper itself

Abstract

purposeVarious global indices are available to summarize results from standard automated perimetry. This study asks which index can detect significant deterioration earliest, for a fixed specificity.

designComparison of prognostic indices.

methodsTwo cohorts were tested. A test-retest cohort contained 5 reliable visual fields, within a short interval, from 45 eyes of 23 participants with glaucoma and/or likelihood of developing glaucoma. A separate longitudinal cohort contained 508 eyes from 330 participants, tested on average 13 times. Three global indices were extracted: mean deviation (MD), pattern standard deviation (PSD), and visual field index (VFI). For each index we defined a critical P value Crit

resultsThe median time to detect significant deterioration with MD was 7.3 years (95% confidence interval [CI] 6.8-7.9 years). For VFI, the median was 8.5 years (95% CI 7.9-9.0 years); this comparison had P = .088. For PSD, the median was 10.5 years (95% CI 9.3-11.7 years), slower than MD with P < .001. Within the first 5 years of a series, MD detected significant deterioration in 138 eyes, vs 104 for VFI (P = .0013) and 107 for PSD (P = .029).

conclusionsMD detected significant deterioration sooner than VFI or PSD. In particular, MD detected more eyes in the first 5 years of their follow-up, which were presumably undergoing more rapid progression.

Indexed as

AgedAged, 80 and overDisease ProgressionFemaleFollow-Up StudiesGlaucoma, Open-AngleHumansMaleMiddle AgedReproducibility of ResultsRetrospective StudiesTime FactorsVision DisordersVisual FieldsVisual Field Tests

Identifiers

PMID28130041
PMCPMC5376527
OpenAlexW2580869318

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.