Evidence map›Paper›PMID 28130022›Full record

ArticleResearch in social & administrative pharmacy : RSAP

Improving over-the-counter medication safety for older adults: A study protocol for a demonstration and dissemination study.

Michelle A Chui, Jamie A Stone, Richard J Holden

Abstract read
In one paragraph

Article in Research in social & administrative pharmacy : RSAP. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Trial
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  8. Prevalence and impact of non-prescription medication misuse in the geriatric population.Exploratory research in clinical and social pharmacy · 2025
    Article
  9. Article
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  15. Using a scenario-based hybrid approach to understand participant health behavior.Research in social & administrative pharmacy : RSAP · 2021
    Article
  16. Human factors and ergonomics methods for pharmacy research and clinical practice.Research in social & administrative pharmacy : RSAP · 2021
    Review
  17. Article
  18. Article
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  20. Applying participatory design to a pharmacy system intervention.Research in social & administrative pharmacy : RSAP · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Michelle A ChuiSystems Approach to Medication Safety Research Laboratory, Social & Administrative Sciences Division, University of Wisconsin - Madison, School of Pharmacy, 777 Highland Avenue, Madison, WI, 53705, United States. Electronic address: michelle.chui@wisc.edu.
Jamie A StoneSystems Approach to Medication Safety Research Laboratory, Social & Administrative Sciences Division, University of Wisconsin - Madison, School of Pharmacy, 777 Highland Avenue, Madison, WI, 53705, United States. Electronic address: jamie.stone@wisc.edu.
Richard J HoldenSchool of Informatics and Computing, Indiana University-Purdue University Indianapolis, 535 W. Michigan Street, IT 475, Indianapolis, IN, 46202, United States. Electronic address: rjholden@iupui.edu.

Funding

Institutional Clinical and Translational Science AwardUL1TR000427 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2012 to 2016
$32.2M
Institutional Clinical and Translational Science AwardKL2TR000428 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2012 to 2016
$6.2M
Improving Over-the-Counter Medication Safety for Older AdultsR18HS024490 · AHRQ · UNIVERSITY OF WISCONSIN-MADISON · PI CHUI, MICHELLE ANNE · 2016 to 2018
$1.4M
A Human Factors Approach to Support Older Chronically Ill Patients' Home CareK01AG044439 · NIA · VANDERBILT UNIVERSITY · PI HOLDEN, RICHARD J · 2014 to 2016
$359k
AHRQ HHS R18 HS024490NCATS NIH HHS KL2 TR000428NCATS NIH HHS UL1 TR000427NIA NIH HHS K01 AG044439
6 · The paper itself

Abstract

backgroundAdverse drug events (ADEs) associated with over-the-counter (OTC) medications cause 178,000 hospitalizations each year. Older adults, aged 65 and older, are particularly vulnerable to ADEs. Of the 2.2 million older adults considered at risk for a major ADE, more than 50% are at risk due to concurrent use of an OTC and prescription medication.

objectivesTo refine the intervention and implementation strategy through diagnostic and formative evaluation; to evaluate the effectiveness of the intervention for preventing misuse of high-risk OTC medications by older adults; and to evaluate the implementation of the intervention in community pharmacies.

methodsA system redesign intervention to decrease high-risk OTC medication misuse will be tested to reduce misuse by improving communication between older adults and community pharmacists via the following features: a redesign of the physical environment to sensitize older adults to high-risk OTC medications, and the implementation of a clinical decision tool to support the pharmacist when critically evaluating the older adult's health status. The study will be conducted in three phases: a participatory design phase, a beta phase, and a test phase. The test phase will be conducted in three mass-merchandise stores. A total of 144 older adults will be recruited. A pre (control)/post (intervention) test will determine the effectiveness of the intervention. The primary outcome will be a comparison of proportion of older adults who misuse OTC medication from baseline to post-intervention. The process of implementation in the community pharmacy setting will be evaluated using the taxonomy proposed by Proctor et al. The participatory design phase has been approved by the institution's IRB (2016-0743). PROJECTED IMPACT: It is anticipated that this project, which focuses on achieving systems-based improvement in an underemphasized area of the medication use process, will reduce ADEs associated with inappropriate OTC medication use in older adults.

Indexed as

Clinical ProtocolsNonprescription DrugsAgedCommunicationDrug InteractionsDrug MisuseDrug-Related Side Effects and Adverse ReactionsHumansPatient SafetyPharmaciesPharmacistsProfessional-Patient RelationsNonprescription DrugsCommunity pharmacyDissemination and implementationHybrid designMedication safetyOlder adults

Identifiers

PMID28130022
PMCPMC5524620

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.