Evidence map›Paper›PMID 28129745›Full record

ArticleBMC cardiovascular disorders2017

Red blood cell distribution width and carotid intima-media thickness in patients with metabolic syndrome.

Dongdong Ren, Juan Wang, Hua Li, Yanyan Li, Zhanzhan Li

Abstract read
In one paragraph

Article in BMC cardiovascular disorders, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Efficacy of low-fat milk and yogurt fortified with vitamin DJournal of health, population, and nutrition · 2022
    Trial
  3. Article
  4. Article
  5. Article
  6. Red Cell Distribution Width as a Novel Prognostic Marker in Multiple Clinical Studies.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2020
    Review
  7. Article
  8. Metabolic syndrome is associated with increased risk of short-term post-procedural complications after carotid artery stenting.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2017
    Article
  9. Review
  10. Article
  11. Red Cell Distribution Width and Elongation Index in a Cohort of Patients With Juvenile Acute Myocardial Infarction.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dongdong RenEmergency Department, Henan Province Hospital of Traditional Chinese Medicine, Zhengzhou, Henan Province, 450002, People's Republic of China.
Juan WangEmergency Department, Henan Province Hospital of Traditional Chinese Medicine, Zhengzhou, Henan Province, 450002, People's Republic of China.
Hua LiEmergency Department, Henan Province Hospital of Traditional Chinese Medicine, Zhengzhou, Henan Province, 450002, People's Republic of China.
Yanyan LiHenan Province Hospital of Traditional Chinese Medicine, Zhengzhou, Henan Province, 450002, People's Republic of China.
Zhanzhan LiDepartment of Oncology, Xiangya Hospital, Central South University, No. 87, Xiangya Road, Changsha, Hunan Province, 410008, People's Republic of China. liche4006@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo evaluate the relationship between red blood cell distribution width (RDW) and carotid intima-media thickness (CIMT) in metabolic syndrome (MetS) patients.

methodsIn this study, we analyzed 803 patients with MetS who underwent carotid ultrasonography examination at Henan Province Hospital of Traditional Chinese Medicine from October 2014 to September 2015. Demographic data were collected using a questionnaire. An automatic biochemistry analyzer measured RDW. Pearson correlation coefficient, multivariate linear and logistic regression was used to evaluate the correlation between RDW and CIMT.

resultsCompared with control group, case group had higher RDW level (P < 0.001) and CIMT (P < 0.001). CIMT was positively related to RDW (r = 0.436, P < 0.001). Logistic regression indicated that RDW was a predictor of CIMT ≥ 1 mm. Compared with the first quartile, people with third and fourth quartile level gave obvious higher risk of carotid artery atherosclerotic trend (OR = 1.41, 95% CI:1.01-197; OR = 2.10, 95% CI: 1.30-3.40). Using a cutoff point of 13.9%, RDW predicts elevated CIMT with a sensitivity of 62.1% and a specificity of 70.3%.

conclusionHigh RDW is related to the increased CIMT in MetS patients, which highlights the role of RDW in the progression of elevated CIMT in MetS patients.

Indexed as

Carotid Intima-Media ThicknessErythrocyte IndicesAdultArea Under CurveCarotid Artery DiseasesChinaChi-Square DistributionCross-Sectional StudiesDisease ProgressionFemaleHumansLinear ModelsLogistic ModelsMaleMetabolic SyndromeMiddle AgedCarotid artery atherosclerosisMetabolic syndromeRed blood cell distribution width

Identifiers

PMID28129745
PMCPMC5273817

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.