ArticleJournal of diabetes investigation2017
The number of microvascular complications is associated with an increased risk for severity of periodontitis in type 2 diabetes patients: Results of a multicenter hospital-based cross-sectional study.
Article in Journal of diabetes investigation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
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Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 46 citations in OpenAlex.
- Prevalence and incidence of infections among people with type 2 diabetes: a systematic review and meta-analysis.Journal of global health · 2026Pooled it
- Diabetic Retinopathy and Periodontitis: Implications from a Systematic Review and Meta-Analysis.International dental journal · 2025Pooled it
- Integrating Oral Health Into Kidney Care: A Policy Imperative for Chronic Kidney Disease, the US Experience.International dental journal · 2026Article
- Effects of periodontitis on micro and macro vascular complications of diabetes: A systematic review.Journal of advanced periodontology & implant dentistry · 2026Article
- Usefulness of the CDC/AAP and the EFP/AAP Criteria to Detect Subclinical Atherosclerosis in Subjects with Diabetes and Severe Periodontal Disease.Diagnostics (Basel, Switzerland) · 2025Article
- The Effect of Subgingival Curcumin Gel With and Without Photodynamic Therapy as Adjunctive Periodontal Treatment in Type 2 Diabetes Mellitus Patients: A Split-Mouth Clinical and Microbiological Study.International journal of dentistry · 2025Article
- The Associations of Dental and Periodontal Lesions with the Microvascular Complications in Patients with Type 2 Diabetes Mellitus: A Case-Control Study.Life (Basel, Switzerland) · 2024Article
- Impacts of Hyperglycemia on Epigenetic Modifications in Human Gingival Fibroblasts and Gingiva in Diabetic Rats.International journal of molecular sciences · 2024Article
- Article
- Establishment of models to predict factors influencing periodontitis in patients with type 2 diabetes mellitus.World journal of diabetes · 2023Article
- The Bidirectional Relationship between Periodontal Disease and Diabetes Mellitus-A Review.Diagnostics (Basel, Switzerland) · 2023Review
- Periodontal diseases assessed by average bone resorption are associated with microvascular complications in patients with type 2 diabetes.Diabetology international · 2023Article
- Potential Therapeutic Applications of Natural Compounds in Diabetes-Associated Periodontitis.Journal of clinical medicine · 2022Review
- Periodontitis, age-related diseases and diabetes in an endocrinological outpatient setting (PARADIES): a cross-sectional analysis on predictive factors for periodontitis in a German outpatient facility.Acta diabetologica · 2022Article
- Personalized and Defect-Specific Antibiotic-Laden Scaffolds for Periodontal Infection Ablation.ACS applied materials & interfaces · 2021Article
- The Outcomes of Enamel Matrix Derivative on Periodontal Regeneration under Diabetic Conditions.Medicina (Kaunas, Lithuania) · 2021Review
- Oral Microbiota: A Major Player in the Diagnosis of Systemic Diseases.Diagnostics (Basel, Switzerland) · 2021Review
- Streptococcus oralis Meningitis with Gingival Bleeding in a Patient: A Case Report and Review of the Literature.Internal medicine (Tokyo, Japan) · 2021Review
- Association between retinopathy, nephropathy, and periodontitis in type 2 diabetic patients: a Meta-analysis.International journal of ophthalmology · 2021Article
- Oral microbiota-induced periodontitis: a new risk factor of metabolic diseases.Reviews in endocrine & metabolic disorders · 2019Review
Corrections and comments
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Authors and funding
50 authors at 20 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
AIMS/
introductionTo explore the relationships between periodontitis and microvascular complications as well as glycemic control in type 2 diabetes patients. MATERIALS AND
methodsThis multicenter, hospital-based, cross-sectional study included 620 patients with type 2 diabetes. We compared the prevalence and severity of periodontitis between patients with ≥1 microvascular complication and those without microvascular complications. We also compared the prevalence and severity of periodontitis among patients with different degrees of glycemic control.
resultsAfter adjusting for confounding factors, multiple logistic regression analysis showed that the severity of periodontitis was significantly associated with the number of microvascular complications (odds ratio 1.3, 95% confidence interval 1.1-1.6), glycated hemoglobin ≥8.0% (64 mmol/mol; odds ratio 1.6; 95% confidence interval 1.1-2.3), and older age (≥50 years; odds ratio 1.7; 95% confidence interval 1.1-2.6). However, the prevalence of periodontitis was not significantly associated with the number of microvascular complications, but was associated with male sex, high glycated hemoglobin (≥8.0% [64 mmol/mol]), older age (≥40 years), longer duration of diabetes (≥15 years) and fewer teeth (≤25). Furthermore, propensity score matching for age, sex, diabetes duration and glycated hemoglobin showed that the incidence of severe periodontitis was significantly higher among patients with microvascular complications than among those without microvascular complications (P < 0.05).
conclusionsThe number of microvascular complications is a risk factor for more severe periodontitis in patients with type 2 diabetes, whereas poor glycemic control is a risk factor for increased prevalence and severity of periodontitis.
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