Evidence map›Paper›PMID 28129208›Full record

ReviewReports on progress in physics. Physical Society (Great Britain)2017

Cell mechanics: a dialogue.

Jiaxiang Tao, Yizeng Li, Dhruv K Vig, Sean X Sun

Abstract readReview
In one paragraph

Review in Reports on progress in physics. Physical Society (Great Britain), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 44 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Modulation of Biofilm Mechanics by DNA Structure and Cell Type.ACS biomaterials science & engineering · 2022
    Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Review
  17. Airway mechanical compression: its role in asthma pathogenesis and progression.European respiratory review : an official journal of the European Respiratory Society · 2020
    Review
  18. Article
  19. Melanoma in the Eyes of Mechanobiology.Frontiers in cell and developmental biology · 2020
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jiaxiang TaoDepartments of Mechanical Engineering, Johns Hopkins University, Baltimore MD, United States of America.
Yizeng LiDepartments of Mechanical Engineering, Johns Hopkins University, Baltimore MD, United States of America.
Dhruv K VigDepartments of Mechanical Engineering, Johns Hopkins University, Baltimore MD, United States of America.
Sean X SunDepartments of Mechanical Engineering, Johns Hopkins University, Baltimore MD, United States of America.
Johns Hopkins University · US

Funding

The Role of Physical Cues in Collective Cell InvasionU54CA210173 · NCI · JOHNS HOPKINS UNIVERSITY · PI SUN, SEAN X · 2016 to 2020
$9.9M
T32: Predoctoral and Postdoctoral Training Program in Nanotechnology for Cancer ResearchT32CA153952 · NCI · JOHNS HOPKINS UNIVERSITY · PI Denis Wirtz · 2015 to 2026
$3.5M
The Role of Osmotic Engine in Confined MigrationR01GM114675 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI KONSTANTOPOULOS, KONSTANTINOS, SUN, SEAN X · 2015 to 2018
$1.3M
T-32 NIH Postdoctoral Training Program in Nanotechnology for Cancer Medicine NTCMT32CA130840 · NCI · JOHNS HOPKINS UNIVERSITY · PI WIRTZ, DENIS · 2008 to 2012
$1.2M
NCI NIH HHS T32 CA130840NCI NIH HHS T32 CA153952NCI NIH HHS U54 CA210173NIGMS NIH HHS R01 GM114675
6 · The paper itself

Abstract

Under the microscope, eukaryotic animal cells can adopt a variety of different shapes and sizes. These cells also move and deform, and the physical mechanisms driving these movements and shape changes are important in fundamental cell biology, tissue mechanics, as well as disease biology. This article reviews some of the basic mechanical concepts in cells, emphasizing continuum mechanics description of cytoskeletal networks and hydrodynamic flows across the cell membrane. We discuss how cells can generate movement and shape changes by controlling mass fluxes at the cell boundary. These mass fluxes can come from polymerization/depolymerization of actin cytoskeleton, as well as osmotic and hydraulic pressure-driven flow of water across the cell membrane. By combining hydraulic pressure control with force balance conditions at the cell surface, we discuss a quantitative mechanism of cell shape and volume control. The broad consequences of this model on cell mechanosensation and tissue mechanics are outlined.

Indexed as

Biomechanical PhenomenaCell Physiological PhenomenaAnimalsCell MovementCytoskeletonModels, BiologicalWaterWater

Identifiers

PMID28129208
PMCPMC5518794
OpenAlexW2581755624

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.