Trial reportLasers in medical science2017
Efficacy and safety of far infrared radiation in lymphedema treatment: clinical evaluation and laboratory analysis.
Trial report in Lasers in medical science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Effectiveness of physical therapy for lower limb lymphedema in gynecological cancer survivors: a systematic review of randomized controlled trials.Frontiers in oncology · 2026Pooled it
- Far-Infrared Radiation to Improve Clinical Outcomes after Arthroscopic Rotator Cuff Repair: A Prospective Randomized Comparative Clinical Study.Clinics in orthopedic surgery · 2023Trial
- Use of a non-medicated plaster in chronic lumbar back pain: a randomized controlled trial.Acta bio-medica : Atenei Parmensis · 2022Trial
- Trial
- Rapid Far-Infrared Radiation and Physiotherapeutic Effects of Carbon Nanotube Flexible Thin-Film Heaters.Nanomaterials (Basel, Switzerland) · 2026Article
- Article
- Effect on Reduction in Inflammatory Fluid and Improvement of Cell Membrane/Skeletal Muscle by Far-Infrared Rays Emitted from Loess Bio-Balls During Sleep.Biomedicines · 2025Article
- Muscle temperature increases during a single far infrared sauna session without changes in intestinal temperature.Journal of applied physiology (Bethesda, Md. : 1985) · 2025Article
- The Effect of Increasing the Body's Core Temperature and Improving Blood Flow by Using Far-Infrared Rays Emitted from Functional Loess Bio-Balls.Biomedicines · 2024Article
- Characteristics of Far-Infrared Ray Emitted from Functional Loess Bio-Balls and Its Effect on Improving Blood Flow.Bioengineering (Basel, Switzerland) · 2024Article
- Impact of risk factors, early rehabilitation and management of lymphedema associated with breast cancer: a retrospective study of breast Cancer survivors over 5 years.BMC women's health · 2024Article
- Efficacy of far infrared functional glasses in the treatment of meibomian gland dysfunction-related dry eye.MedComm · 2024Article
- The Convergence of FTIR and EVs: Emergence Strategy for Non-Invasive Cancer Markers Discovery.Diagnostics (Basel, Switzerland) · 2022Review
- Biology of Lymphedema.Biology · 2021Review
- The effect of postoperatively applied far-infrared radiation on pain and tendon-to-bone healing after arthroscopic rotator cuff repair: a clinical prospective randomized comparative study.The Korean journal of pain · 2020Article
- Article
- Lymphedema diagnosis, treatment, and follow-up from the view point of physical medicine and rehabilitation specialists.Turkish journal of physical medicine and rehabilitation · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 6 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Swelling is the most common symptom of extremities lymphedema. Clinical evaluation and laboratory analysis were conducted after far infrared radiation (FIR) treatment on the main four components of lymphedema: fluid, fat, protein, and hyaluronan. Far infrared radiation is a kind of hyperthermia therapy with several and additional benefits as well as promoting microcirculation flow and improving collateral lymph circumfluence. Although FIR therapy has been applied for several years on thousands of lymphedema patients, there are still few studies that have reported the biological effects of FIR on lymphatic tissue. In this research, we investigate the effects of far infrared rays on the major components of lymphatic tissue. Then, we explore the effectiveness and safety of FIR as a promising treatment modality of lymphedema. A total of 32 patients affected by lymphedema in stage II and III were treated between January 2015 and January 2016 at our department. After therapy, a significant decrease of limb circumference measurements was noted and improving of quality of life was registered. Laboratory examination showed the treatment can also decrease the deposition of fluid, fat, hyaluronan, and protein, improving the swelling condition. We believe FIR treatment could be considered as both an alternative monotherapy and a useful adjunctive to the conservative or surgical lymphedema procedures. Furthermore, the real and significant biological effects of FIR represent possible future applications in wide range of the medical field.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.