Evidence map›Paper›PMID 28127569›Full record

ArticleJournal of immunology research2017

Association of Toll-Like Receptor 3 Single-Nucleotide Polymorphisms and Hepatitis C Virus Infection.

Mashael R Al-Anazi, Sabine Matou-Nasri, Ayman A Abdo, Faisal M Sanai, Saad Alkahtani, Saud Alarifi, Abdullah A Alkahtane, Hamad Al-Yahya, Daoud Ali, Mohammed S Alessia and 3 more

Open access · goldAbstract read
In one paragraph

Article in Journal of immunology research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. TLR3 Gene Polymorphism in HCV Infection in the Kazakh Population of Western Kazakhstan.Asian Pacific journal of cancer prevention : APJCP · 2023
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Functional Polymorphisms inBioMed research international · 2018
    Article
  12. Viruses Seen by Our Cells: The Role of Viral RNA Sensors.Journal of immunology research · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Mashael R Al-AnaziDepartment of Infection and Immunity, Research Center, King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia.
Sabine Matou-NasriCell and Gene Therapy Group, Medical Genomics Research Department, King Abdullah International Medical Research Center, Ministry of National Guard, Riyadh, Saudi Arabia.
Ayman A AbdoSection of Gastroenterology, Department of Medicine, College of Medicine, King Saud University, Riyadh, Saudi Arabia; Liver Disease Research Center, King Saud University, Riyadh, Saudi Arabia.
Faisal M SanaiLiver Disease Research Center, King Saud University, Riyadh, Saudi Arabia; Gastroenterology Unit, Department of Medicine, King Abdulaziz Medical City, Jeddah, Saudi Arabia.
Saad AlkahtaniDepartment of Zoology, Science College, King Saud University, Riyadh, Saudi Arabia.
Saud AlarifiDepartment of Zoology, Science College, King Saud University, Riyadh, Saudi Arabia.
Abdullah A AlkahtaneDepartment of Zoology, Science College, King Saud University, Riyadh, Saudi Arabia.
Hamad Al-YahyaDepartment of Zoology, Science College, King Saud University, Riyadh, Saudi Arabia.
Daoud AliDepartment of Zoology, Science College, King Saud University, Riyadh, Saudi Arabia.
Mohammed S AlessiaDepartment of Biology, Science College, AI-Imam Muhammad Ibn Saud Islamic University, Riyadh, Saudi Arabia.
Bushra AlshahraniDepartment of Infection and Immunity, Research Center, King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia.
Mohammed N Al-AhdalDepartment of Infection and Immunity, Research Center, King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia; Department of Microbiology and Immunology, Alfaisal University School of Medicine, Riyadh, Saudi Arabia.
Ahmed A Al-QahtaniDepartment of Infection and Immunity, Research Center, King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia; Department of Microbiology and Immunology, Alfaisal University School of Medicine, Riyadh, Saudi Arabia.ORCID 0000-0003-4584-5739
King Saud University · SAAlfaisal University · SAKing Faisal Specialist Hospital & Research Centre · SAImam Mohammad ibn Saud Islamic University · SAKing Abdullah International Medical Research Center · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Toll-like receptor 3 (TLR3) plays a key role in innate immunity by recognizing pathogenic, double-stranded RNAs. Thus, activation of TLR3 is a major factor in antiviral defense and tumor eradication. Although downregulation of

Indexed as

AdultAgedCarcinoma, HepatocellularFemaleFibrosisGenetic Association StudiesGenetic Predisposition to DiseaseGenotypeHepatitis C, ChronicHumansLiver NeoplasmsMaleMiddle AgedPolymorphism, Single NucleotideRiskSaudi ArabiaTLR3 protein, humanToll-Like Receptor 3

Identifiers

PMID28127569
PMCPMC5239973
OpenAlexW2566119273

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.