Evidence map›Paper›PMID 28127562›Full record

ArticleBioMed research international2017

Declining Physical Performance Associates with Serum FasL, miR-21, and miR-146a in Aging Sprinters.

Reeta Kangas, Timo Törmäkangas, Ari Heinonen, Markku Alen, Harri Suominen, Vuokko Kovanen, Eija K Laakkonen, Marko T Korhonen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BioMed research international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Non-coding RNAs in exercise immunology: A systematic review.Journal of sport and health science · 2024
    Pooled it
  2. Pooled it
  3. Article
  4. sFasL-The Key to a Riddle: Immune Responses in Aging Lung and Disease.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Reeta KangasGerontology Research Center, Department of Health Sciences, University of Jyvaskyla, Jyvaskyla, Finland.ORCID 0000-0002-3633-5238
Timo TörmäkangasGerontology Research Center, Department of Health Sciences, University of Jyvaskyla, Jyvaskyla, Finland.ORCID 0000-0001-7268-5297
Ari HeinonenGerontology Research Center, Department of Health Sciences, University of Jyvaskyla, Jyvaskyla, Finland.ORCID 0000-0002-3681-9953
Markku AlenDepartment of Medical Rehabilitation, Oulu University Hospital, Oulu, Finland; Center for Life Course Health Research, University of Oulu, Oulu, Finland.
Harri SuominenGerontology Research Center, Department of Health Sciences, University of Jyvaskyla, Jyvaskyla, Finland.
Vuokko KovanenGerontology Research Center, Department of Health Sciences, University of Jyvaskyla, Jyvaskyla, Finland.
Eija K LaakkonenGerontology Research Center, Department of Health Sciences, University of Jyvaskyla, Jyvaskyla, Finland.ORCID 0000-0001-6655-9489
Marko T KorhonenGerontology Research Center, Department of Health Sciences, University of Jyvaskyla, Jyvaskyla, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aging is associated with systemic inflammation and cellular apoptosis accelerating physiological dysfunctions. Whether physically active way of life affects these associations is unclear. This study measured the levels of serum inflammatory and apoptotic molecules, their change over 10 years, and their associations with physical performance in sprint-trained male athletes. HsCRP, cell counts, HGB, FasL, miR-21, and miR-146a were measured cross-sectionally (

Indexed as

AdolescentAdultAgedAged, 80 and overAgingBiomarkersCross-Sectional StudiesFas Ligand ProteinFollow-Up StudiesHumansInflammation MediatorsMaleMicroRNAsMiddle AgedPhysical FitnessRunningBiomarkersFASLG protein, humanFas Ligand ProteinInflammation MediatorsMicroRNAsMIRN146 microRNA, humanMIRN21 microRNA, human

Identifiers

PMID28127562
PMCPMC5239835

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.