Evidence map›Paper›PMID 28127534›Full record

ArticleKorean journal of orthodontics2017

Incorporation of silver nanoparticles on the surface of orthodontic microimplants to achieve antimicrobial properties.

Adith Venugopal, Nallal Muthuchamy, Harsh Tejani, Anantha-Iyengar Gopalan, Kwang-Pill Lee, Heon-Jin Lee, Hee Moon Kyung

Open access · bronzeAbstract read
In one paragraph

Article in Korean journal of orthodontics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 60 citations in OpenAlex.

  1. Pooled it
  2. Use of Antimicrobial Silver Coatings on Fixed Orthodontic Appliances, Including Archwires, Brackets, and Microimplants: A Systematic Review.Medical science monitor : international medical journal of experimental and clinical research · 2024
    Pooled it
  3. Review
  4. Review
  5. Article
  6. Usage of Silver Nanoparticles in Orthodontic Appliances.Materials (Basel, Switzerland) · 2025
    Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. On the Use of Nanoparticles in Dental Implants.Materials (Basel, Switzerland) · 2024
    Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Applications of Gold and Silver Nanoparticles in Theranostics.Applied biochemistry and biotechnology · 2022
    Review
  17. Review
  18. Nanoparticles in Dentistry: A Comprehensive Review.Pharmaceuticals (Basel, Switzerland) · 2021
    Review
  19. Review
  20. Nanomaterials Application in Orthodontics.Nanomaterials (Basel, Switzerland) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Adith VenugopalDepartment of Orthodontics, School of Dentistry, Kyungpook National University, Daegu, Korea.
Nallal MuthuchamyDepartment of Chemistry Education, Kyungpook National University, Daegu, Korea.
Harsh TejaniDepartment of Orthodontics, School of Dentistry, Kyungpook National University, Daegu, Korea.
Anantha-Iyengar GopalanResearch Institute of Advanced Energy Technology, Kyungpook National University, Daegu, Korea.; Department of Nanoscience and Nanotechnology, Kyungpook National University, Daegu, Korea.
Kwang-Pill LeeDepartment of Chemistry Education, Kyungpook National University, Daegu, Korea.; Research Institute of Advanced Energy Technology, Kyungpook National University, Daegu, Korea.; Department of Nanoscience and Nanotechnology, Kyungpook National University, Daegu, Korea.
Heon-Jin LeeDepartment of Oral Microbiology and Immunology, Kyungpook National University, Daegu, Korea.
Hee Moon KyungDepartment of Orthodontics, School of Dentistry, Kyungpook National University, Daegu, Korea.
Kyungpook National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveMicrobial aggregation around dental implants can lead to loss/loosening of the implants. This study was aimed at surface treating titanium microimplants with silver nanoparticles (AgNPs) to achieve antibacterial properties.

methodsAgNP-modified titanium microimplants (Ti-nAg) were prepared using two methods. The first method involved coating the microimplants with regular AgNPs (Ti-AgNP) and the second involved coating them with a AgNP-coated biopolymer (Ti-BP-AgNP). The topologies, microstructures, and chemical compositions of the surfaces of the Ti-nAg were characterized by scanning electron microscopy (SEM) equipped with energy-dispersive spectrometer (EDS) and X-ray photoelectron spectroscopy (XPS). Disk diffusion tests using

resultsSEM revealed that only a meager amount of AgNPs was sparsely deposited on the Ti-AgNP surface with the first method, while a layer of AgNP-coated biopolymer extended along the Ti-BP-AgNP surface in the second method. The diameters of the coated nanoparticles were in the range of 10 to 30 nm. EDS revealed 1.05 atomic % of Ag on the surface of the Ti-AgNP and an astounding 21.2 atomic % on the surface of the Ti-BP-AgNP. XPS confirmed the metallic state of silver on the Ti-BP-AgNP surface. After 24 hours of incubation, clear zones of inhibition were seen around the Ti-BP-AgNP microimplants in all three test bacterial culture plates, whereas no antibacterial effect was observed with the Ti-AgNP microimplants.

conclusionsTitanium microimplants modified with Ti-BP-AgNP exhibit excellent antibacterial properties, making them a promising implantable biomaterial.

Indexed as

AntimicrobialMicroimplantNanosilver

Identifiers

PMID28127534
PMCPMC5266125
OpenAlexW2574126895

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.