ArticleBrain and behavior2017
Side-of-onset of Parkinson's disease in relation to neuropsychological measures.
Article in Brain and behavior, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- A novel rat model of body first subtype of Parkinson's disease.bioRxiv : the preprint server for biology · 2026Article
- Differences in Spatial Cognition and Motor-Cognitive Integration by Side of Onset in People with Parkinson's Disease.Brain sciences · 2026Article
- Machine learning classification of early-stage Parkinson's disease using sit-to-walk biomechanical features.Scientific reports · 2026Article
- Impact of motor symptom asymmetry on non-motor outcomes in Parkinson's disease: a systematic review.NPJ Parkinson's disease · 2025Article
- Investigation of the voice handicaps in Parkinson's disease and determination of the clinical correlates.Journal of neural transmission (Vienna, Austria : 1996) · 2025Article
- Non-motor asymmetry and dopamine degeneration in Parkinson's disease.Brain communications · 2025Article
- Exploring the cognitive assessment potential of MRI-based volumetric hippocampal segmentation in Parkinson's disease.Brain and behavior · 2024Article
- Imbalanced motivated behaviors according to motor sign asymmetry in drug-naïve Parkinson's disease.Scientific reports · 2023Article
- Moderating effects of uric acid and sex on cognition and psychiatric symptoms in asymmetric Parkinson's disease.Biology of sex differences · 2023Article
- Mapping microstructural gradients of the human striatum in normal aging and Parkinson's disease.Science advances · 2022Article
- Investigating the relationship between the SNCA gene and cognitive abilities in idiopathic Parkinson's disease using machine learning.Scientific reports · 2021Article
- The enigma and implications of brain hemispheric asymmetry in neurodegenerative diseases.Brain communications · 2021Review
- Motor Symptom Lateralization Influences Cortico-Striatal Functional Connectivity in Parkinson's Disease.Frontiers in neurology · 2021Article
- Abnormal Spontaneous Brain Activity in Left-Onset Parkinson Disease: A Resting-State Functional MRI Study.Frontiers in neurology · 2020Article
- The Relationship between Side of Onset and Cerebral Regional Homogeneity in Parkinson's Disease: A Resting-State fMRI Study.Parkinson's disease · 2020Article
- The Choice of Leg During Pull Test in Parkinson's Disease: Not Mere Chance.Frontiers in neurology · 2020Article
- Symptom Dimensions of Depression and Apathy and Their Relationship With Cognition in Parkinson's Disease.Journal of the International Neuropsychological Society : JINS · 2018Article
- Side-of-onset of Parkinson's disease in relation to neuropsychological measures.Brain and behavior · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundParkinson's disease (PD) usually emerges with a unilateral side-of-onset (left-onset: LOPD; right-onset: ROPD; Marinus & van Hilten, 2015) due to an asymmetrical degeneration of striatal dopaminergic neurons (Donnemiller et al.,
methodsThirty ROPD and 14 LOPD cases were drawn from a Boston clinic specializing in PD. Various cognitive and neuropsychological measures were used in an attempt to discover if there were indeed any differences between LOPD and ROPD in this cohort.
resultsFor LOPD, duration of illness was found to be significantly greater than that of ROPD. However, further testing was able to confirm that despite this difference, it was not the cause of the other significant differences found. Furthermore, this increased duration was consistent with a previous study (Munhoz et al.,
conclusionClear and significant differences between LOPD and ROPD were found within our cohort. LOPD showed greater impairment of working memory, greater anxiety, and greater duration of illness-all independent of one another; whereas, those with ROPD had greater magical ideation, also independent of any other variables.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.