Evidence map›Paper›PMID 28127473›Full record

ArticleCase reports in critical care2017

Hemadsorption with Adult CytoSorb® in a Low Weight Pediatric Case.

Catalin Gabriel Cirstoveanu, Ileana Barascu, Samantha Mc Kenzie Stancu

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in critical care, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

  1. Novel extracorporeal therapies in children.Pediatric nephrology (Berlin, Germany) · 2026
    Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Hemoperfusion with CytoSorbJournal of clinical medicine · 2024
    Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Catalin Gabriel Cirstoveanu"Carol Davila" University of Medicine & Pharmacy Bucharest, 37 Dionisie Lupu Street, District 1, 020021 Bucharest, Romania; "Marie S. Curie Children's Emergency Hospital" Bucharest, Neonatal Intensive Care Unit, 20 Constantin Brancoveanu Street, District 4, 041451 Bucharest, Romania.ORCID 0000-0002-7778-0477
Ileana Barascu"Marie S. Curie Children's Emergency Hospital" Bucharest, Neonatal Intensive Care Unit, 20 Constantin Brancoveanu Street, District 4, 041451 Bucharest, Romania.
Samantha Mc Kenzie Stancu"Carol Davila" University of Medicine & Pharmacy Bucharest, 37 Dionisie Lupu Street, District 1, 020021 Bucharest, Romania.
Carol Davila University of Medicine and Pharmacy · ROSpitalului Clinic de Urgență pentru Copii Maria Sklodowska Curie · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cytokine adsorber (CytoSorb) has been used successfully as adjunctive treatment for adult patients with elevated cytokine levels in the setting with severe sepsis and septic shock and to reduce blood myoglobin, unconjugated bilirubin, and conjugated bilirubin. In this article we present the case of a nine-month-old male infant who was admitted to the NICU due to sepsis after cardiac surgery, Fallot tetralogy, and multisystem organ failure (MSOF) including liver failure and renal failure which was successfully treated by a combination of continuous hemodiafiltration (HDF) and hemadsorption with CytoSorb. HDF was safe and effective from the first day for urea removal, but the patient's bilirubin levels kept increasing gradually, culminating on the 9th day with a maximum value of 54 mg/dL of total bilirubin and 31.67 mg/dL of direct bilirubin when we performed hemadsorption with CytoSorb. Over the 49-hour period of hemadsorption, the total bilirubin value decreased from 54 to 14 mg/dL, and the patient's general status improved considerably accompanied by a rapid drop of aminotransferases. Hemodynamic status has been improved as well and inotropes dropped rapidly. The patient's ventilation settings improved during CytoSorb treatment permitting weaning the patient from mechanical ventilation after five days of hemadsorption. The patient was discharged home after 34 days of hospitalization, in a good general status.

Identifiers

PMID28127473
PMCPMC5239828
OpenAlexW2566634752

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.