ArticleKorean Journal of Spine2016
Effective Response of Methotrexate for Recurrent Idiopathic Hypertrophic Spinal Pachymeningitis.
Article in Korean Journal of Spine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed, 8 citations in OpenAlex.
- Idiopathic Hypertrophic Pachymeningitis with Elevated Anti-Thyroglobulin Antibodies-A Case Report.Reports (MDPI) · 2025Article
- Idiopathic Hypertrophic Spinal Pachymeningitis.Journal of medical cases · 2023Article
- Idiopathic Hypertrophic Spinal Pachymeningitis with Spinal Cord Lesion: A Case Report.Korean journal of neurotrauma · 2020Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Idiopathic hypertrophic spinal pachymeningitis (IHSP) is a chronic progressive and diffuse inflammatory fibrosis of the spinal dura mater. Though treatment of IHSP is surgical decompression with steroid therapy, treatment for recurrent IHSP is controversial. Our patient was diagnosed with IHSP based on magnetic resonance imaging (MRI) and underwent laminectomy for decompression following steroid pulse therapy. Despite maintenance of steroid therapy, the patient experienced 3 recurrences. As an alternative immunosuppressant medication, methotrexate was introduced with low-dose steroid. Fortunately, the symptom was resolved, and a decrease of dura thickening was revealed on MRI. We present the case and suggest that methotrexate might be an effective treatment modality for recurrent IHSP.
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Registered trials
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