Evidence map›Paper›PMID 28127054›Full record

SynthesisScientific reports2017

Association of alcohol intake with risk of diabetic retinopathy: a meta-analysis of observational studies.

Wei Zhu, Yi-Fang Meng, Yan Wu, Ming Xu, Jiong Lu

Open access · goldAbstract readMeta-Analysis
In one paragraph

Synthesis in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 7 pooled it
10.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 7 syntheses or guidelines pooled it, 86 citations in OpenAlex.

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  19. Alcohol and the Eye.Journal of ophthalmic & vision research
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Wei ZhuDepartment of Ophthalmology, Changshu NO. 2 People's Hospital, Changshu, China.
Yi-Fang MengDepartment of Ophthalmology, Changshu NO. 2 People's Hospital, Changshu, China.
Yan WuDepartment of Ophthalmology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Ming XuDepartment of Ophthalmology, Changshu NO. 2 People's Hospital, Changshu, China.
Jiong LuDepartment of Ophthalmology, Changshu NO. 2 People's Hospital, Changshu, China. cslujiong@163.com.
Changshu No.1 People's Hospital · CNChangshu No. 2 People's HospitalSoochow University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetic retinopathy (DR) is a common microvascular complication of diabetes mellitus (DM). The associations of alcohol intake with DR risk have demonstrated contradictory results. Relevant studies were identified by searching electronic databases (Medline, EMBASE and Web of Science) until May 2016. We identified a total of 12,875 DR cases among 37,285 participants in 15 observational studies. The pooled estimation of all the included observational studies was 0.91 (95% CI, 0.79 to 1.06) in a random-effect model. Analyses stratified by study design showed no significant association between alcohol intake and DR incidence in cohort, case control or cross-sectional studies. In the subgroup analyses, neither beer nor spirits intake were associated with DR risk. Furthermore, it was interesting to find that protective effects were detected in the wine (OR = 0.77, 95% CI = 0.64 to 0.92) and sherry (OR = 0.22, 95% CI = 0.05 to 0.95) groups. In conclusion, this current meta-analysis demonstrated that alcohol intake was not associated with risk of DR. Subgroup analysis by alcoholic beverage types showed that wine consumption would reduce the incidence of DR. In the future, more large-scale prospective studies with detailed alcohol subtypes and contents are still warranted to clarify the association.

Indexed as

AdultAgedAged, 80 and overAlcohol DrinkingCross-Sectional StudiesDiabetic RetinopathyHumansMiddle AgedProspective StudiesRisk AssessmentYoung Adult

Identifiers

PMID28127054
PMCPMC5428369
OpenAlexW2582719690

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.