Evidence map›Paper›PMID 28126963›Full record

ArticleHaematologica2017

Plasma-derived proteomic biomarkers in human leukocyte antigen-haploidentical or human leukocyte antigen-matched bone marrow transplantation using post-transplantation cyclophosphamide.

Christopher G Kanakry, Giorgos Bakoyannis, Susan M Perkins, Shannon R McCurdy, Ante Vulic, Edus H Warren, Etienne Daguindau, Taylor Olmsted, Christen Mumaw, Andrea M H Towlerton and 5 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Haematologica, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 35 citations in OpenAlex.

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  17. Biomarkers for Allogeneic HCT Outcomes.Frontiers in immunology · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 1 country.

Christopher G KanakrySidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, MD.
Giorgos BakoyannisDepartment of Biostatistics, Indiana University School of Medicine, Indianapolis, IN.
Susan M PerkinsDepartment of Biostatistics, Indiana University School of Medicine, Indianapolis, IN.
Shannon R McCurdySidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, MD.
Ante VulicSidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, MD.
Edus H WarrenClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA.
Etienne DaguindauDepartment of Pediatrics, Indiana University School of Medicine, Indianapolis, IN.
Taylor OlmstedDepartment of Pediatrics, Indiana University School of Medicine, Indianapolis, IN.
Christen MumawDepartment of Pediatrics, Indiana University School of Medicine, Indianapolis, IN.
Andrea M H TowlertonClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA.
Kenneth R CookeSidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, MD.
Paul V O'DonnellClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA.
Heather J SymonsSidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, MD.
Sophie PaczesnyDepartment of Pediatrics, Indiana University School of Medicine, Indianapolis, IN luznile@jhmi.edu sophpacz@iu.edu.
Leo LuznikSidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, MD luznile@jhmi.edu sophpacz@iu.edu.
Indiana University School of MedicineJohns Hopkins University · USFred Hutch Cancer Center · USIndiana University – Purdue University Indianapolis · USSidney Kimmel Comprehensive Cancer Center · US

Funding

Translating Novel Drug-Targetable Biomarkers to Treat Graft versus Host DiseaseR01CA168814 · NCI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI PACZESNY, SOPHIE · 2013 to 2024
$3.0M
MECHANISMS OF GVHD PREVENTION WITH POST-TRANSPLANT CYCLOPHOSPHAMIDER01HL110907 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI LUZNIK, LEO, WARREN, EDUS HOUSTON · 2012 to 2015
$1.7M
NCI NIH HHS R01 CA168814NHLBI NIH HHS R01 HL110907
6 · The paper itself

Abstract

Recent studies have suggested that plasma-derived proteins may be potential biomarkers relevant for graft-

Indexed as

AdultAgedAntineoplastic Agents, AlkylatingBiomarkersBone Marrow TransplantationCyclophosphamideFemaleGraft vs Host DiseaseHematologic NeoplasmsHistocompatibility TestingHLA AntigensHumansInterleukin-1 Receptor-Like 1 ProteinInterleukin-2 Receptor alpha SubunitMaleMiddle AgedAntineoplastic Agents, AlkylatingBiomarkersCyclophosphamideHLA AntigensIL1RL1 protein, humanInterleukin-1 Receptor-Like 1 ProteinInterleukin-2 Receptor alpha SubunitPancreatitis-Associated ProteinsReceptors, Tumor Necrosis Factor, Type IREG3A protein, human

Identifiers

PMID28126963
PMCPMC5477612
OpenAlexW2579912490

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.