Evidence map›Paper›PMID 28126961›Full record

Trial reportHaematologica2017

miR-125b and miR-532-3p predict the efficiency of rituximab-mediated lymphodepletion in chronic lymphocytic leukemia patients. A French Innovative Leukemia Organization study.

Anne-Laure Gagez, Isabelle Duroux-Richard, Stéphane Leprêtre, Frédérique Orsini-Piocelle, Rémi Letestu, Sophie De Guibert, Edouard Tuaillon, Véronique Leblond, Olfa Khalifa, Valérie Gouilleux-Gruart and 6 more

Open access · goldAbstract readClinical Trial, Phase IIRandomized Controlled Trial
In one paragraph

Trial report in Haematologica, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Review
  3. miRNAs in Lymphocytic Leukaemias-The miRror of Drug Resistance.International journal of molecular sciences · 2022
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Non-Coding RNAs as Cancer Hallmarks in Chronic Lymphocytic Leukemia.International journal of molecular sciences · 2020
    Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Plasma exosome-derived microRNA-532 as a novel predictor for acute myeloid leukemia.Cancer biomarkers : section A of Disease markers · 2020
    Article
  14. Review
  15. Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 14 institutions in 1 country.

Anne-Laure GagezCNRS UMR 5235, University of Montpellier, France.
Isabelle Duroux-RichardINSERM, U1183, Institute of Regenerative Medicine and Biotherapy, University Hospital Montpellier, France.
Stéphane LeprêtreHenri Becquerel Center, Rouen, France.
Frédérique Orsini-PiocelleDepartment of Clinical Hematology, Hospital Center of Annecy, Pringy, France.
Rémi LetestuDepartment of Biological Hematology, APHP, GHUPSSD, Avicenne Hospital, Bobigny, France.
Sophie De GuibertDepartment of Clinical Hematology, Pontchaillou Hospital, Rennes, France.
Edouard TuaillonDepartment of Bacteriology-Virology, University Hospital Montpellier, France.
Véronique LeblondDepartment of Hematology, La Pitié Salpétrière Hospital, Paris, France.
Olfa KhalifaINSERM, U1183, Institute of Regenerative Medicine and Biotherapy, University Hospital Montpellier, France.
Valérie Gouilleux-GruartCNRS UMR 7292, François Rabelais University, University Hospital Tours, France.
Anne BanosDepartment of Hematology, Cote Basque Hospital, Bayonne, France.
Olivier TournilhacDepartment of Clinical Hematology, University Hospital Estaing, Clermont-Ferrand, France.
Jehan DupuisUnit of Lymphoid Hematologic Malignancies, Henri Mondor Hospital, Créteil, France.
Christian JorgensenINSERM, U1183, Institute of Regenerative Medicine and Biotherapy, University Hospital Montpellier, France.
Guillaume CartronCNRS UMR 5235, University of Montpellier, France g-cartron@chu-montpellier.fr.
Florence ApparaillyINSERM, U1183, Institute of Regenerative Medicine and Biotherapy, University Hospital Montpellier, France.
Inserm · FRAssistance Publique – Hôpitaux de Paris · FRCentre Hospitalier de la Côte Basque · FRCentre Hospitalier Universitaire de Clermont-Ferrand · FRCentre Hospitalier Universitaire de Rennes · FRClinique Ambroise Paré · FRHôpital Arnaud de Villeneuve · FRHôpital Avicenne · FRHôpital Lapeyronie · FRHôpitaux Universitaires Henri-Mondor · FRLaboratoire National Henri Becquerel · FRLaboratory of Pathogens and Host Immunity · FRUniversité de Montpellier · FRUniversité de Tours · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The underlying

Indexed as

Lymphocyte DepletionAntineoplastic Combined Chemotherapy ProtocolsBiomarkers, TumorCluster AnalysisDiagnosis, DifferentialFemaleGene Expression Regulation, LeukemicGenotypeHumansLeukemia, Lymphocytic, Chronic, B-CellLymphocytosisMaleMicroRNAsMiddle AgedModels, BiologicalPrognosisBiomarkers, TumorMicroRNAsMIRN125 microRNA, humanMIRN532 microRNA, humanRituximab

Identifiers

PMID28126961
PMCPMC5395115
OpenAlexW2581703858

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.